Evidence map›Paper›PMID 25651056›Full record

ArticleStructure (London, England : 1993)2015

Basis of cargo recognition by importin αs: the power of structure.

Gualtiero Alvisi, David A Jans

Abstract readComment
PubMed Publisher
In one paragraph

Article in Structure (London, England : 1993), 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

2 authors.

Gualtiero AlvisiDepartment of Molecular Medicine, University of Padua, 35121 Padua, Italy.
David A JansDepartment of Biochemistry and Molecular Biology, Monash University, Clayton, VIC 3800, Australia. Electronic address: david.jans@monash.edu.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In this issue of Structure, Pumroy and colleagues have solved the crystal structure of the influenza virus polymerase PB2 C-terminal domain complexed with different Importin αs. Combining molecular dynamics with structural and biochemical data, the so-far elusive basis for selectivity of binding to distinct different importin αs is beginning to become accessible.

Indexed as

Evolution, MolecularModels, Molecularalpha KaryopherinsCell NucleusHumansNuclear Localization SignalsRNA-Dependent RNA PolymeraseViral Proteinsalpha KaryopherinsNuclear Localization SignalsRNA-Dependent RNA PolymeraseViral Proteins

Identifiers

What OpenQuestion holds

Textmetadata
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.