ArticlePediatric critical care medicine : a journal of the Society of Critical Care Medicine and the World Federation of Pediatric Intensive and Critical Care Societies2015
Functional recovery following critical illness in children: the "wee-cover" pilot study.
Article in Pediatric critical care medicine : a journal of the Society of Critical Care Medicine and the World Federation of Pediatric Intensive and Critical Care Societies, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
29 citing papers in PubMed, 65 citations in OpenAlex.
- Use of selective gut decontamination in critically ill children: PICnIC a pilot RCT and mixed-methods study.Health technology assessment (Winchester, England) · 2024Trial
- Selective digestive tract decontamination to prevent healthcare associated infections in critically ill children: the PICNIC multicentre randomised pilot clinical trial.Scientific reports · 2023Trial
- Impact of critical illness and withholding of early parenteral nutrition in the pediatric intensive care unit on long-term physical performance of children: a 4-year follow-up of the PEPaNIC randomized controlled trial.Critical care (London, England) · 2022Trial
- Early Protocolized Versus Usual Care Rehabilitation for Pediatric Neurocritical Care Patients: A Randomized Controlled Trial.Pediatric critical care medicine : a journal of the Society of Critical Care Medicine and the World Federation of Pediatric Intensive and Critical Care Societies · 2019Trial
- Long-Term Outcomes after Protocolized Sedation versus Usual Care in Ventilated Pediatric Patients.American journal of respiratory and critical care medicine · 2018Trial
- Prevalence and magnitude of muscle loss in the pediatric intensive care unit assessed by ultrasound: a systematic review and meta-analysis.Jornal de pediatria · 2026Review
- Validation of the BioIntelliSense BioButton® device for physical activity monitoring in children and future application as a physical health outcome for critically Ill children.Frontiers in pediatrics · 2025Article
- Early predictors of unfavorable outcomes in pediatric acute respiratory failure.Journal of intensive care · 2024Article
- Implementing early rehabilitation and mobilisation for children in UK paediatric intensive care units: the PERMIT feasibility study.Health technology assessment (Winchester, England) · 2023Article
- PICU Survivorship: Factors Affecting Feasibility and Cohort Retention in a Long-Term Outcomes Study.Children (Basel, Switzerland) · 2022Article
- Chronic critical illness and post-intensive care syndrome: from pathophysiology to clinical challenges.Annals of intensive care · 2022Review
- Article
- Building a culture of early mobilization in the pediatric intensive care unit-a nuts and bolts approach.Translational pediatrics · 2021Review
- Physical Functioning After Admission to the PICU: A Scoping Review.Critical care explorations · 2021Article
- Article
- Normal Baseline Function Is Associated With Delayed Rehabilitation in Critically Ill Children.Journal of intensive care medicine · 2020Article
- Long-term Sequelae of Pediatric Neurocritical Care: The Parent Perspective.Journal of pediatric intensive care · 2018Article
- Multistakeholder Qualitative Research Methods to Impact Culture of Care Practices in the ICU.Pediatric critical care medicine : a journal of the Society of Critical Care Medicine and the World Federation of Pediatric Intensive and Critical Care Societies · 2018Article
- Mortality After Pediatric Critical Illness: Made It Home, Still Vulnerable.Pediatric critical care medicine : a journal of the Society of Critical Care Medicine and the World Federation of Pediatric Intensive and Critical Care Societies · 2018Article
- Body Composition Changes in Severely Burned Children During ICU Hospitalization.Pediatric critical care medicine : a journal of the Society of Critical Care Medicine and the World Federation of Pediatric Intensive and Critical Care Societies · 2017Article
Corrections and comments
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Authors and funding
12 authors at 2 institutions in 2 countries.
Funding
Abstract
objectiveTo determine the feasibility of conducting a longitudinal prospective study to evaluate functional recovery and predictors of impaired functional recovery in critically ill children.
designProspective pilot study.
settingSingle-center PICU at McMaster Children's Hospital, Hamilton, Canada. PATIENTS: Children aged 12 months to 17 years, with at least one organ dysfunction, limited mobility or bed rest during the first 48 hours of PICU admission, and a minimum 48-hour PICU length of stay, were eligible. Patients transferred from a neonatal ICU prior to ever being discharged home, already mobilizing well or at baseline functional status at time of screening, with an English language barrier, and prior enrollment into this study, were excluded.
interventionsNone. MEASUREMENTS AND MAIN
resultsThe primary outcome was feasibility, as defined by the ability to screen, enroll eligible patients, and execute the study procedures and measurements on participants. Secondary outcomes included functional status at baseline, 3 and 6 months, PICU morbidity, and mortality. Functional status was measured using the Pediatric Evaluation of Disability Inventory and the Participation and Environment Measure for Children and Youth. Thirty-three patients were enrolled between October 2012 and April 2013. Consent rate was 85%, and follow-up rates were 93% at 3 months and 71% at 6 months. We were able to execute the study procedures and measurements, demonstrating feasibility of conducting a future longitudinal study. Functional status deteriorated following critical illness. Recovery appears to be influenced by baseline health or functional status and severity of illness.
conclusionLongitudinal research is needed to understand how children recover after a critical illness. Our results suggest factors that may influence the recovery trajectory and were used to inform the methodology, outcomes of interest, and appropriate sample size of a larger multicenter study evaluating functional recovery in this population.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.