ArticleJournal of the American Association for Laboratory Animal Science : JAALAS2014
Characterization of rat pinworm (Syphacia muris) epidemiology as a means to increase detection and elimination.
Article in Journal of the American Association for Laboratory Animal Science : JAALAS, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
14 citing papers in PubMed, 27 citations in OpenAlex.
- Observations on the transmission ofParasitology · 2024Article
- Potential anthelmintic effect of chitosan on Syphacia muris infecting Wistar rats: biochemical, immunological, and histopathological studies.Scientific reports · 2024Article
- In vivo efficacy of silver nanoparticles againstJournal of parasitic diseases : official organ of the Indian Society for Parasitology · 2023Article
- Research-Relevant Conditions and Pathology of Laboratory Mice, Rats, Gerbils, Guinea Pigs, Hamsters, Naked Mole Rats, and Rabbits.ILAR journal · 2021Review
- In vitro and in vivo anthelmintic study ofJournal of parasitic diseases : official organ of the Indian Society for Parasitology · 2021Article
- PCR and RT-PCR in the Diagnosis of Laboratory Animal Infections and in Health Monitoring.Journal of the American Association for Laboratory Animal Science : JAALAS · 2020Article
- Low-cost, Small-scale Decontamination of Laboratory Equipment by Using Chlorine Dioxide Gas.Journal of the American Association for Laboratory Animal Science : JAALAS · 2019Article
- PCR Testing of IVC Filter Tops as a Method for Detecting Murine Pinworms and Fur Mites.Journal of the American Association for Laboratory Animal Science : JAALAS · 2017Article
- Evaluation of Anthelmintic Resistance and Exhaust Air Dust PCR as a Diagnostic Tool in Mice Enzootically Infected withJournal of the American Association for Laboratory Animal Science : JAALAS · 2017Article
- Population genetics, community of parasites, and resistance to rodenticides in an urban brown rat (Rattus norvegicus) population.PloS one · 2017Article
- Evaluation of Traditional and Contemporary Methods for DetectingJournal of the American Association for Laboratory Animal Science : JAALAS · 2017Article
- Guidance Regarding Sample Collection and Refinement of Fecal Flotation Exam for the Isolation of Aspiculuris tetraptera.Journal of the American Association for Laboratory Animal Science : JAALAS · 2016Article
- Morphological and Molecular Analysis ofIranian journal of parasitologyArticle
- Article
Corrections and comments
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Authors and funding
2 authors at 1 institution in 1 country.
Funding
Abstract
Rodent pinworms persist in many institutions, suggesting deficiencies in eradication and diagnostic processes. When pinworms are detected, treatment success is common, but false-negative test results during health surveillance or after treatment likely contribute to the continued presence of this parasite. PCR testing is not always practical, and increased information regarding the life cycle and general epidemiology of pinworm infestations could improve the sensitivity of traditional nonPCR detection methods and improve eradication efforts. We therefore investigated a pinworm (Syphacia muris) infestation in Sprague-Dawley rats (Rattus norvegicus) to develop a more accurate testing strategy. In addition, we sought to determine the duration of egg viability by using an in vitro hatching protocol to assess environmental persistence. Finally, we tested the ovicidal efficacy of a disinfectant used at our institution. Eggs were shed in higher numbers in the midafternoon as compared with other times of the day, and the sex of the host had no consistent effect on egg shedding. Egg shedding showed periodicity over time, with shedding decreasing to 0 at 2- to 3-wk intervals. Neither cecal examination nor tape tests alone reliably predicted pinworm infestation, and results of the 2 tests did not necessarily coincide. Eggs aged for as long as 7 mo remained viable, indicating a potential for recontamination from the environment. Finally, gaseous chlorine dioxide was an effective ovicidal agent, with a kill rate of 99.7%. These results suggest that strategies for S. muris eradication can be optimized to increase detection and elimination.
Indexed as
Identifiers
25650973PMC4253580W215164569What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.