Evidence map›Paper›PMID 25650902›Full record

ArticleNature structural & molecular biology2015

Synergistic activation of Toll-like receptor 8 by two RNA degradation products.

Matthias Geyer, Karin Pelka, Eicke Latz

Abstract readComment
PubMed Publisher
In one paragraph

Article in Nature structural & molecular biology, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed.

  1. Article
  2. Article
  3. Suppression ofFrontiers in molecular biosciences · 2021
    Article
  4. Article
  5. Article
  6. Article
  7. Identification of an optimized 2'-RNA (New York, N.Y.) · 2017
    Article
  8. Article
  9. Nucleic acid-sensing TLRs: trafficking and regulation.Current opinion in immunology · 2017
    Review
  10. Review
  11. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

3 authors.

Matthias Geyer1] Institute of Innate Immunity, University Clinics Bonn, University of Bonn, Germany. [2] Center of Advanced European Studies and Research (CAESAR), Bonn, Germany.
Karin PelkaInstitute of Innate Immunity, University Clinics Bonn, University of Bonn, Germany.
Eicke Latz1] Institute of Innate Immunity, University Clinics Bonn, University of Bonn, Germany. [2] Department of Infectious Diseases and Immunology, University of Massachusetts Medical School, Worcester, Massachusetts, USA, the German Center for Neurodegenerative Diseases (DZNE), Bonn, Germany, and the Centre of Molecular Inflammation Research, Department of Cancer Research and Molecular Medicine, Norwegian University of Science and Technology, Trondheim, Norway.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

AnimalsHumansRNAToll-Like Receptor 8RNATLR8 protein, humanToll-Like Receptor 8

Identifiers

PMID25650902

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.