Evidence map›Paper›PMID 25650316›Full record

ArticleJournal of the National Cancer Institute2015

The case for conducting a randomized clinical trial to assess the efficacy of a single dose of prophylactic HPV vaccines among adolescents.

Aimée R Kreimer, Mark E Sherman, Vikrant V Sahasrabuddhe, Mahboobeh Safaeian

Abstract readComparative Study
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of the National Cancer Institute, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Trial
  3. Trial
  4. Article
  5. Article
  6. Review
  7. Article
  8. Article
  9. National- and state-level impact and cost-effectiveness of nonavalent HPV vaccination in the United States.Proceedings of the National Academy of Sciences of the United States of America · 2016
    Article
  10. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Aimée R KreimerDivision of Cancer Epidemiology and Genetics, Infections and Immunoepidemiology Branch (ARK, MS), Division of Cancer Prevention, Breast and Gynecologic Cancer Research Group (MES, VVS), Division of Cancer Epidemiology and Genetics, Human Genetics Program (MES), and Division of Cancer Epidemiology and Genetics, Hormonal and Reproductive Epidemiology Branch (VVS), National Cancer Institute, National Institutes of Health, Bethesda, MD; Department of Medicine, Vanderbilt University School of Medicine, Nashville, TN (VVS). kreimera@mail.nih.gov.
Mark E ShermanDivision of Cancer Epidemiology and Genetics, Infections and Immunoepidemiology Branch (ARK, MS), Division of Cancer Prevention, Breast and Gynecologic Cancer Research Group (MES, VVS), Division of Cancer Epidemiology and Genetics, Human Genetics Program (MES), and Division of Cancer Epidemiology and Genetics, Hormonal and Reproductive Epidemiology Branch (VVS), National Cancer Institute, National Institutes of Health, Bethesda, MD; Department of Medicine, Vanderbilt University School of Medicine, Nashville, TN (VVS).
Vikrant V SahasrabuddheDivision of Cancer Epidemiology and Genetics, Infections and Immunoepidemiology Branch (ARK, MS), Division of Cancer Prevention, Breast and Gynecologic Cancer Research Group (MES, VVS), Division of Cancer Epidemiology and Genetics, Human Genetics Program (MES), and Division of Cancer Epidemiology and Genetics, Hormonal and Reproductive Epidemiology Branch (VVS), National Cancer Institute, National Institutes of Health, Bethesda, MD; Department of Medicine, Vanderbilt University School of Medicine, Nashville, TN (VVS).
Mahboobeh SafaeianDivision of Cancer Epidemiology and Genetics, Infections and Immunoepidemiology Branch (ARK, MS), Division of Cancer Prevention, Breast and Gynecologic Cancer Research Group (MES, VVS), Division of Cancer Epidemiology and Genetics, Human Genetics Program (MES), and Division of Cancer Epidemiology and Genetics, Hormonal and Reproductive Epidemiology Branch (VVS), National Cancer Institute, National Institutes of Health, Bethesda, MD; Department of Medicine, Vanderbilt University School of Medicine, Nashville, TN (VVS).

Funding

Intramural NIH HHS
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Randomized Controlled Trials as TopicAdolescentCost-Benefit AnalysisDose-Response Relationship, DrugFemaleHumansImmunization SchedulePapillomavirus InfectionsPapillomavirus VaccinesResearch DesignUnited StatesUterine Cervical NeoplasmsPapillomavirus Vaccines

Identifiers

PMID25650316
PMCPMC4326307

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.