ArticleClinical medicine (London, England)2015
Rabies: the clinical features, management and prevention of the classic zoonosis.
Article in Clinical medicine (London, England), 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
18 citing papers in PubMed.
- Nationwide registry-based analysis of rabies exposures in Iran: Epidemiological patterns and post-exposure prophylaxis adherence.PLoS neglected tropical diseases · 2026Article
- Surveillance of Humans Exposed to the Potentially Rabid Animals and Rabies Post-Exposure Prophylaxis in Split-Dalmatia County, Croatia, 2015-2024.Medicina (Kaunas, Lithuania) · 2025Article
- Article
- Establishment of serological neutralizing tests using pseudotyped viruses for comprehensive detection of antibodies against all 18 lyssaviruses.The Journal of veterinary medical science · 2024Article
- Recent updates on laboratory diagnosis of rabies.The Indian journal of medical research · 2024Review
- Tracking lethal threat: in-depth review of rabies.Open veterinary journal · 2023Review
- Defining County-Level Terrestrial Rabies Freedom Using the US National Rabies Surveillance System: Surveillance Data Analysis.JMIR public health and surveillance · 2023Article
- Evaluation of country infrastructure as an indirect measure of dog-mediated human rabies deaths.Frontiers in veterinary science · 2023Article
- "When a dog bites someone": Community and service provider dynamics influencing access to integrated bite case management in Chad.Frontiers in veterinary science · 2022Article
- Rabies encephalitis.BMJ case reports · 2021Article
- The rabies distribution pattern on dogs using average nearest neighbor analysis approach in the Karangasem District, Bali, Indonesia, in 2019.Veterinary world · 2021Article
- Article
- Article
- A dog bite study in a dog rabies-affected area in South Africa.Southern African journal of infectious diseases · 2020Article
- Human rabies post exposure prophylaxis at the Pasteur Institute of Dakar, Senegal: trends and risk factors.BMC infectious diseases · 2019Article
- Management of dog bites by frontline service providers in primary healthcare facilities in the Greater Accra Region of Ghana, 2014-2015.Infectious diseases of poverty · 2018Article
- The Importance of a Participatory and Integrated One Health Approach for Rabies Control: The Case of N'Djaména, Chad.Tropical medicine and infectious disease · 2017Article
- The rabies early death phenomenon: A report of ineffective administration of rabies vaccine during symptomatic disease.Indian journal of critical care medicine : peer-reviewed, official publication of Indian Society of Critical Care Medicine · 2015Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The diagnosis of rabies encephalitis relies on awareness of the varied clinical features and eliciting a history of unusual contact with a mammal throughout the endemic area. The diagnosis is easily missed. Laboratory tests are not routine and only confirm clinical suspicion. Rabies infection carries a case fatality exceeding 99.9%. Palliation is appropriate, except for previously-vaccinated patients or those infected by American bats, for whom intensive care is probably indicated. However, as rabies vaccines are outstandingly effective, no one should die of dog-transmitted infection. Vaccines and rabies immunoglobulin are expensive and usually scarce in Asia and Africa. All travellers to dog rabies enzootic areas should be strongly encouraged to have pre-exposure immunisation before departure. There is no contraindication to vaccination but the cost can be prohibitive. Intradermal immunisation, using 0.1 ml and sharing vials of vaccine, is cheaper and is now permitted by UK regulations. Returning travellers may need post-exposure prophylaxis. Economical intradermal post-exposure vaccination is practicable and should be introduced into rural areas of Africa and Asia immediately. Eliminating rabies in dogs is now feasible and would dramatically reduce human mortality, if funds were made available. The high current economic burden of human prophylaxis would then be largely relieved.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.