Evidence map›Paper›PMID 25650092›Full record

ArticleLeukemia2015

Blocking programmed cell death 1 in combination with adoptive cytotoxic T-cell transfer eradicates chronic myelogenous leukemia stem cells.

C Riether, T Gschwend, A-L Huguenin, C M Schürch, A F Ochsenbein

Open access · hybridAbstract readLetter
In one paragraph

Article in Leukemia, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed
1.3field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 34 citations in OpenAlex.

  1. Article
  2. Review
  3. Novel targeted therapies in chronic myeloid leukemia.Pharmaceutical science advances · 2024
    Review
  4. Prognostic Significance of Regulatory T-Cells and PD-1 + CD8 T-Cells in Chronic Myeloid Leukemia Patients Treated with Generic Imatinib.Indian journal of hematology & blood transfusion : an official journal of Indian Society of Hematology and Blood Transfusion · 2024
    Article
  5. Leukemic Stem Cells and Hematological Malignancies.International journal of molecular sciences · 2024
    Review
  6. Article
  7. Review
  8. Article
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  10. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

C RietherDepartment of Clinical Research, Tumor Immunology, University of Bern, Bern, Switzerland.
T GschwendDepartment of Clinical Research, Tumor Immunology, University of Bern, Bern, Switzerland.
A-L HugueninDepartment of Clinical Research, Tumor Immunology, University of Bern, Bern, Switzerland.
C M Schürch1] Department of Clinical Research, Tumor Immunology, University of Bern, Bern, Switzerland [2] Institute of Pathology, University of Bern, Bern, Switzerland.
A F Ochsenbein1] Department of Clinical Research, Tumor Immunology, University of Bern, Bern, Switzerland [2] Department of Medical Oncology, Inselspital, University Hospital and University of Bern, Bern, Switzerland.
University of Bern · CH

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Cell- and Tissue-Based TherapyAdoptive TransferAnimalsApoptosisCell ProliferationCells, CulturedLeukemia, Myelogenous, Chronic, BCR-ABL PositiveMiceMice, Inbred C57BLNeoplastic Stem CellsProgrammed Cell Death 1 ReceptorT-Lymphocytes, CytotoxicPdcd1 protein, mouseProgrammed Cell Death 1 Receptor

Identifiers

PMID25650092
PMCPMC4530202
OpenAlexW2062313719

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-SA
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.