Evidence map›Paper›PMID 25649496›Full record

ArticleDental materials : official publication of the Academy of Dental Materials2015

The use of micro-CT with image segmentation to quantify leakage in dental restorations.

Carola A Carrera, Caixia Lan, David Escobar-Sanabria, Yuping Li, Joel Rudney, Conrado Aparicio, Alex Fok

Open access · greenAbstract read
In one paragraph

Article in Dental materials : official publication of the Academy of Dental Materials, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 33 papers.

0numbers the graph read from it
0cells of the map it votes in
33citing papers in PubMed
8.4field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

33 citing papers in PubMed, 89 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Carola A CarreraMinnesota Dental Research Center for Biomaterials and Biomechanics, School of Dentistry, University of Minnesota, Minneapolis, MN, USA.
Caixia LanMinnesota Dental Research Center for Biomaterials and Biomechanics, School of Dentistry, University of Minnesota, Minneapolis, MN, USA.
David Escobar-SanabriaDepartment of Aerospace Engineering and Mechanics, University of Minnesota, Minneapolis, MN, USA.
Yuping LiMinnesota Dental Research Center for Biomaterials and Biomechanics, School of Dentistry, University of Minnesota, Minneapolis, MN, USA.
Joel RudneyDepartment of Diagnostic and Biological Sciences, School of Dentistry, University of Minnesota, Minneapolis, MN, USA.
Conrado AparicioMinnesota Dental Research Center for Biomaterials and Biomechanics, School of Dentistry, University of Minnesota, Minneapolis, MN, USA.
Alex FokMinnesota Dental Research Center for Biomaterials and Biomechanics, School of Dentistry, University of Minnesota, Minneapolis, MN, USA. Electronic address: alexfok@umn.edu.
University of Minnesota · US

Funding

Interactions Between Oral Biofilms and Dental Resin CompositesR01DE021366 · NIDCR · UNIVERSITY OF MINNESOTA · PI FOK, ALEX SIU-LUN, JONES, ROBERT SIMON · 2010 to 2013
$1.5M
NIDCR NIH HHS 1 R01 DE021366NIDCR NIH HHS R01 DE021366
6 · The paper itself

Abstract

objectiveTo develop a method for quantifying leakage in composite resin restorations after curing, using non-destructive X-ray micro-computed tomography (micro-CT) and image segmentation.

methodsClass-I cavity preparations were made in 20 human third molars, which were divided into 2 groups. Group I was restored with Z100 and Group II with Filtek LS. Micro-CT scans were taken for both groups before and after they were submerged in silver nitrate solution (AgNO3 50%) to reveal any interfacial gap and leakage at the tooth restoration interface. Image segmentation was carried out by first performing image correlation to align the before- and after-treatment images and then by image subtraction to isolate the silver nitrate penetrant for precise volume calculation. Two-tailed Student's t-test was used to analyze the results, with the level of significance set at p<0.05.

resultsAll samples from Group I showed silver nitrate penetration with a mean volume of 1.3 ± 0.7mm(3). In Group II, only 2 out of the 10 restorations displayed infiltration along the interface, giving a mean volume of 0.3 ± 0.3mm(3). The difference between the two groups was statistically significant (p<0.05). The infiltration showed non-uniform patterns within the interface. SIGNIFICANCE: We have developed a method to quantify the volume of leakage using non-destructive micro-CT, silver nitrate infiltration and image segmentation. Our results confirmed that substantial leakage could occur in composite restorations that have imperfections in the adhesive layer or interfacial debonding through polymerization shrinkage. For the restorative systems investigated in this study, this occurred mostly at the interface between the adhesive system and the tooth structure.

Indexed as

Dental Restoration, PermanentComposite ResinsDental BondingDental Cavity PreparationDental LeakageHumansIn Vitro TechniquesMolar, ThirdSilver NitrateX-Ray MicrotomographyComposite ResinsSilver NitrateComposite resinsDental adhesivesInterfacial debondingLeakageMicro-CTSecondary caries

Identifiers

PMID25649496
PMCPMC4374050
OpenAlexW2011729285

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.