Observational studyHealth and quality of life outcomes2015
Preoperative and early postoperative quality of life after major surgery - a prospective observational study.
Observational study in Health and quality of life outcomes, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
20 citing papers in PubMed, 1 synthesis or guideline pooled it.
- The Role of Preoperative Parenteral Nutrition.Nutrients · 2020Pooled it
- Association of Obesity With Septic Complications After Major Abdominal Surgery: A Secondary Analysis of the RELIEF Randomized Clinical Trial.JAMA network open · 2019Trial
- Commentary: Development and validation of a multivariate predictive model for cancer-related fatigue in esophageal carcinoma: a prospective cohort study integrating biomarkers and psychosocial factors.Frontiers in oncology · 2026Article
- Improving the Quality of Life of Gynecological Patients with Surgery: A Cross-Sectional Study Based on Questionnaire Surveys.Medicina (Kaunas, Lithuania) · 2025Article
- Preoperative ANemiA among elderly undergoing Major Abdominal surgery (PANAMA) is associated with early postoperative morbidity and worse quality of life outcomes.Scientific reports · 2025Observational
- Healing beyond bone: a qualitative study of the core decompression experience of physically active patients with stage II hip avascular necrosis.Journal of orthopaedic surgery and research · 2025Article
- Emotional Stress and Immune Response in Surgery: A Psychoneuroimmunological Perspective.Cureus · 2023Review
- A longitudinal assessment of appetite loss and nutritional care among postoperative patients in Vietnam.Frontiers in nutrition · 2023Article
- Association of metabolic equivalent of task (MET) score in length of stay in hospital following radical cystectomy with urinary diversion: a multi-institutional study.International urology and nephrology · 2021Article
- Patient reported outcomes in an elder-friendly surgical environment: Prospective, controlled before-after study.Annals of medicine and surgery (2012) · 2021Article
- Impact of Perioperative Complications on Living Kidney Donor Health-Related Quality of Life and Mental Health: Results From a Prospective Cohort Study.Canadian journal of kidney health and disease · 2021Article
- A Pragmatic Non-Randomized Trial of Prehabilitation Prior to Cancer Surgery: Study Protocol and COVID-19-Related Adaptations.Frontiers in oncology · 2021Article
- An investigation of the effect of patient-controlled analgesia on long-term quality of life after major surgery: A prospective cohort study.Journal of the Chinese Medical Association : JCMA · 2020Article
- Minor effect of loss to follow-up on outcome interpretation in the Swedish spine register.European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society · 2020Article
- Determining the effectiveness of fibrin sealants in reducing complications in patients undergoing lateral neck dissection (DEFeND): study protocol for a randomised external pilot trial.Pilot and feasibility studies · 2020Article
- Long-term quality of life and posttraumatic stress following elective cardiac surgery: preliminary findings of a 5-year follow-up study.Acta medica Lituanic · 2019Article
- Wireless Monitoring Program of Patient-Centered Outcomes and Recovery Before and After Major Abdominal Cancer Surgery.JAMA surgery · 2017Article
- Changes in quality of life after elective surgery: an observational study comparing two measures.Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation · 2017Observational
- Physical activity trends as predictors of postoperative complications in oncology patients: A machine learning approach.Digital healthArticle
- Physiological and operative severity score for the enumeration of mortality and morbidity, frailty, and perioperative quality of life in the elderly.Saudi journal of anaesthesiaArticle
Corrections and comments
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Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundChanges in health-related quality of life (HRQoL) several days after surgery have rarely been investigated. We aimed to estimate the perioperative change of HRQoL, to identify patients with clinically relevant decrease in postoperative HRQoL and to establish factors associated with this decrease in HRQoL at day 30 after major surgery.
methodsPatients scheduled for major surgery at a university hospital were enrolled. Based on the HRQoL SF-12 questionnaire, the preoperative physical component summary (PCS) score, preoperative mental component summary (MCS) score, and postoperative PCS and MCS scores at day 30 were recorded. Minimal clinically important difference (MCID) was defined as those with a decrease of at least one half of the standard deviation (SD) of preoperative PCS or MCS scores. Differences between the groups with or without decreased HRQoL were investigated using univariate comparisons. A multiple logistic regression model was performed to evaluate the predictive value of potential perioperative variables.
resultsThe mean ± SD preoperative PCS score was 38.5 ± 10.6, postoperative score was 35.1 ± 7.8 (p = .004) in 85 patients. Thirty-five patients (41.2%) had a clinically relevant decrease of the postoperative PCS score. A normal to high preoperative exercise metabolic capacity measured with metabolic equivalent of task (MET) (p = .01) was a predictor of the decrease in postoperative PCS. The mean preoperative MCS scores (p = .395) were 42.2 (SD 12.8) preoperative, and 43.45 (SD 12.4) postoperative, respectively.
conclusionsMajor surgery decreases postoperative PCS scores of HRQoL at 30 days. A normal to high exercise capacity was a predictor of a clinically relevant decrease of postoperative PCS scores.
trial registration07-107 (Ethical Committee NAC of Geneva University Hospitals).
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