ArticleBMC public health2015
No evidence of decline in malaria burden from 2006 to 2013 in a rural Province of Gabon: implications for public health policy.
Article in BMC public health, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06172686 (Adaptation of Blood-stage Controlled Human Malaria Infection for Evaluation of Transmission Blocking Malaria Interventions in Malaria Endemic Countries), which is not on this map. Cited by 23 papers.
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The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Adaptation of Blood-stage Controlled Human Malaria Infection for Evaluation of Transmission Blocking Malaria Interventions in Malaria Endemic Countries
Who cites it
23 citing papers in PubMed.
- IgG antibody response against Plasmodium falciparum aminopeptidase 1 antigen in Gabonese children living in Makokou and Franceville.Clinical and experimental immunology · 2020Trial
- Spatio-temporal heterogeneity of urban malaria in Libreville, Gabon (2012-2023): neighborhood-level hotspot analysis for micro-stratified control.Malaria journal · 2026Article
- Burden and determinants of asymptomatic malaria among adults living in urban and rural areas in Gabon in 2023: a community-based cross-sectional study.Malaria journal · 2025Article
- Malaria Prevention for Pregnant Women and Under-Five Children in 10 Sub-Saharan Africa Countries: Socioeconomic and Temporal Inequality Analysis.International journal of environmental research and public health · 2024Article
- Malaria Prevalence in Asymptomatic and Symptomatic Children Living in Rural, Semi-Urban and Urban Areas in Eastern Gabon.Acta parasitologica · 2024Article
- Bayesian spatio-temporal analysis of malaria prevalence in children between 2 and 10 years of age in Gabon.Malaria journal · 2024Article
- Severe malaria in children and adolescents in Southeast Gabon.BMC infectious diseases · 2023Article
- Decrease on malaria clinical cases from 2017 to 2019 in Franceville, Southeast Gabon, Central Africa.Journal of public health in Africa · 2023Article
- Epidémiology of malaria from 2019 to 2021 in the southeastern city of Franceville, Gabon.BMC public health · 2022Article
- Inflammatory cytokine responses in children with asymptomatic malaria infection living in rural, semi-urban and urban areas in south-eastern Gabon.Clinical and experimental immunology · 2021Article
- The effect of malaria on haemoglobin concentrations: a nationally representative household fixed-effects study of 17,599 children under 5 years of age in Burkina Faso.Malaria journal · 2021Article
- Differential Prevalences ofInfection and drug resistance · 2021Article
- Article
- Malaria in children and women of childbearing age: infection prevalence, knowledge and use of malaria prevention tools in the province of Nyanga, Gabon.Malaria journal · 2020Article
- High Circulation of Malaria and Low Prevalence of Bacteremia in Febrile and Afebrile Children in Northeastern Gabon.The American journal of tropical medicine and hygiene · 2020Article
- Implementing population-based mass drug administration for malaria: experience from a high transmission setting in North Eastern Uganda.Malaria journal · 2019Article
- Characterization of Plasmodium infections among inhabitants of rural areas in Gabon.Scientific reports · 2019Article
- Prevalence of and risk factors for malaria, filariasis, and intestinal parasites as single infections or co-infections in different settlements of Gabon, Central Africa.Infectious diseases of poverty · 2018Article
- Demography, maternal health and the epidemiology of malaria and other major infectious diseases in the rural department Tsamba-Magotsi, Ngounie Province, in central African Gabon.BMC public health · 2017Article
- Comparative Antibody Responses Against three Antimalarial Vaccine Candidate Antigens from Urban and Rural Exposed Individuals in Gabon.European journal of microbiology & immunology · 2016Article
Corrections and comments
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Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundThe morbidity of malaria has steady declined in the urban regions of Gabon between 2000 and 2008, but caution should be exercised before generalizing this trend to the whole country because this finding has not been systematically confirmed in remote rural provinces.
methodsWe conducted a retrospective survey using data on malaria cases recorded in North Eastern Gabon between 2006 and 2013 at health facilities in Makokou. Malaria data were analyzed, and associations with annual variations and patient age were assessed.
resultsA global increase in clinical and confirmed malaria cases was observed over the study period. The rate of infection was significantly higher in children aged between 0 to 4 years than in children of 5 years and above, and in adults. Contrary to prior observations in urban and semi-urban areas of Gabon, malaria burden remained mostly unchanged or even increased in Makokou in the Ogooué-Ivindo province during these last 8 years.
conclusionsThe persistence of Plasmodium falciparum pockets of sustained malaria transmission in rural Gabon may be related to an inadequate coverage of key interventions, to poor treatment seeking behavior and/or to a decline efficacy of treatments. Our results highlight the need to better adapt malaria control strategies to local epidemiological contexts and to environmental constraints. Equitable delivery of health service to hard-to-reach populations constitutes a challenging issue for the health authorities of Gabon.
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