Evidence map›Paper›PMID 25649042›Full record

ArticleBMJ (Clinical research ed.)2015

Alternate Healthy Eating Index 2010 and risk of chronic obstructive pulmonary disease among US women and men: prospective study.

Raphaëlle Varraso, Stephanie E Chiuve, Teresa T Fung, R Graham Barr, Frank B Hu, Walter C Willett, Carlos A Camargo

Open access · hybridAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in BMJ (Clinical research ed.), 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 106 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
106citing papers in PubMed, 3 pooled it
15.9field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

106 citing papers in PubMed, 3 syntheses or guidelines pooled it, 225 citations in OpenAlex.

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46 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

7 authors at 5 institutions in 2 countries.

Raphaëlle VarrasoINSERM U1168, VIMA (Aging and chronic diseases. Epidemiological and public health approaches), 16 avenue Paul Vaillant Couturier, 94 807 Villejuif, France UVSQ, UMR-S 1168, Université Versailles St-Quentin-en-Yvelines, France raphaelle.varraso@inserm.fr.
Stephanie E ChiuveDivision of Preventive Medicine, Department of Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, MA 02215, USA Department of Nutrition, Harvard School of Public Health, Boston, MA 02115, USA.
Teresa T FungDepartment of Nutrition, Harvard School of Public Health, Boston, MA 02115, USA Department of Nutrition, Simmons College, Boston, MA 02115, USA.
R Graham BarrDivision of General Medicine, Department of Medicine, and Department of Epidemiology, Columbia University Medical Center, New York, NY 10032, USA.
Frank B HuDepartment of Nutrition, Harvard School of Public Health, Boston, MA 02115, USA Channing Division of Network Medicine, Department of Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, MA 02115, USA Department of Epidemiology, Harvard School of Public Health, Boston, MA 02115, USA.
Walter C WillettDepartment of Nutrition, Harvard School of Public Health, Boston, MA 02115, USA Channing Division of Network Medicine, Department of Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, MA 02115, USA Department of Epidemiology, Harvard School of Public Health, Boston, MA 02115, USA.
Carlos A CamargoChanning Division of Network Medicine, Department of Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, MA 02115, USA Department of Epidemiology, Harvard School of Public Health, Boston, MA 02115, USA Department of Emergency Medicine, Massachusetts General Hospital, Boston, MA 02114, USA.
Harvard University · USBrigham and Women's Hospital · USColumbia University Irving Medical Center · USSimmons University · USUniversité de Versailles Saint-Quentin-en-Yvelines · FR

Funding

Statistical MethodsP01CA087969 · NCI · BRIGHAM AND WOMEN'S HOSPITAL · PI ROSNER, BERNARD A · 2000 to 2019
$77.8M
Cancer Epidemiology Cohort in Male Health ProfessionalsU01CA167552 · NCI · HARVARD UNIVERSITY D/B/A HARVARD SCHOOL OF PUBLIC HEALTH · PI Lorelei Mucci, Walter C. Willett · 2017 to 2026
$17.0M
Cancer Epidemiology Cohort in Male Health ProfessionalsUM1CA167552 · NCI · HARVARD SCHOOL OF PUBLIC HEALTH · PI WILLETT, WALTER C. · 2012 to 2016
$11.5M
Fish Oil Intake, Biomarkers and Change in Lung FunctionR01HL075476 · NHLBI · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI BARR, R GRAHAM · 2004 to 2008
$2.8M
DIET AND CHRONIC OBSTRUCTIVE PULMONARY DISEASER01HL063841 · NHLBI · BRIGHAM AND WOMEN'S HOSPITAL · PI CAMARGO, CARLOS A. · 2000 to 2002
$1.0M
Hormonal and Inflammatory Markers in Adult-onset AsthmaR21AI052338 · NIAID · BRIGHAM AND WOMEN'S HOSPITAL · PI CAMARGO, CARLOS A. · 2003 to 2003
$304k
NCI NIH HHS CA-167552NCI NIH HHS CA-87969NHLBI NIH HHS HL-63841NHLBI NIH HHS R01 HL075476NIAID NIH HHS AI-52338
6 · The paper itself

Abstract

objectiveTo investigate the association between the Alternate Healthy Eating Index 2010 (AHEI-2010)--a measure of diet quality--and the risk of chronic obstructive pulmonary disease (COPD).

designProspective cohort study.

settingParticipants in the Nurses' Health Study and the Health Professionals Follow-up Study, United States.

participants73,228 female nurses from 1984 to 2000 and 47,026 men from 1986 to 1998, who completed biennial questionnaires.

main outcome measuresThe primary outcome was the self report of newly diagnosed COPD. Multivariable Cox proportional hazards models were adjusted for age, physical activity, body mass index, total energy intake, smoking, second hand tobacco exposure (only in the Nurses' Health Study), race/ethnicity, physician visits, US region, spouse's highest educational attainment (only in the Nurses' Health Study), and menopausal status (only in the Nurses' Health Study).

resultsOver the study period, 723 cases of newly diagnosed COPD occurred in women and 167 in men. In the pooled analysis, a significant negative association was seen between the risk of newly diagnosed COPD and fifths of the AHEI-2010: hazard ratios were 0.81 (95% confidence interval 0.51 to 1.29) for the second fifth, 0.98 (0.80 to 1.18) for the third fifth, 0.74 (0.59 to 0.92) for the fourth fifth, and 0.67 (0.53 to 0.85) for participants who ate the healthiest diet according to the AHEI-2010 (that is, were in the highest fifth), compared with those who ate the less healthy diet (participants in the lowest fifth). Similar findings were observed among ex-smokers and current smokers.

conclusionsA higher AHEI-2010 diet score (reflecting high intakes of whole grains, polyunsaturated fatty acids, nuts, and long chain omega-3 fats and low intakes of red/processed meats, refined grains, and sugar sweetened drinks) was associated with a lower risk of COPD in both women and men. These findings support the importance of a healthy diet in multi-interventional programs to prevent COPD.

Indexed as

AdultAgedAsthmaDietFeeding BehaviorFemaleHumansIncidenceMaleMiddle AgedProportional Hazards ModelsProspective StudiesPulmonary Disease, Chronic ObstructiveRisk FactorsSurveys and QuestionnairesUnited States

Identifiers

PMID25649042
PMCPMC4707519
OpenAlexW2164541899

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.