Observational studyAmerican journal of obstetrics and gynecology2015
A description of the methods of the Nulliparous Pregnancy Outcomes Study: monitoring mothers-to-be (nuMoM2b).
Observational study in American journal of obstetrics and gynecology, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 205 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Preterm Birth in Nulliparous Women: An Understudied Population at Great Risk
Imaging Innovations for Placental Assessment in Response to Environmental Pollution
Who cites it
205 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- Association of Genetic Predisposition and Physical Activity With Risk of Gestational Diabetes in Nulliparous Women.JAMA network open · 2022Pooled it
- Universal late pregnancy ultrasound screening to predict adverse outcomes in nulliparous women: a systematic review and cost-effectiveness analysis.Health technology assessment (Winchester, England) · 2021Pooled it
- Analytical approaches to evaluating hypertensive disorders of pregnancy.American journal of obstetrics & gynecology MFM · 2023Trial
- Sleep-disordered Breathing in Pregnancy and after Delivery: Associations with Cardiometabolic Health.American journal of respiratory and critical care medicine · 2022Trial
- Web-Based Quality Assurance Process Drives Improvements in Obstetric Ultrasound in 5 Low- and Middle-Income Countries.Global health, science and practice · 2016Trial
- Racial and Ethnic Differences in Nonresponse Rate to Experiences of Discrimination: A Secondary Analysis of the nuMoM2b Dataset.Research in nursing & health · 2026Article
- Health behavior profiles in early pregnancy are associated with adverse pregnancy outcomes and maternal blood pressure 2-7 years after delivery.American journal of preventive cardiology · 2026Article
- Prenatal exposure to DEHTP replacement metabolites and odds of preeclampsia and gestational hypertension in a diverse nulliparous U.S. cohort.Environmental advances · 2026Article
- Maternal and offspring genome-wide association study of C-reactive protein reveals limited polygenic association with gestational diabetes mellitus.BMC genomics · 2026Article
- Prepregnancy Diet Quality Index and Adverse Pregnancy Outcomes.JAMA network open · 2026Article
- Early Pregnancy Body Roundness Index and Development of Adverse Pregnancy Outcomes: A Secondary Analysis of the nuMoM2b Study.Obesity (Silver Spring, Md.) · 2026Observational
- Factors Associated With Leisure Time Physical Activity and Sedentary Behavior in Young Women 2-7 Years After Delivery of a Pregnancy in the nuMoM2b Heart Health Study.American journal of health promotion : AJHP · 2026Article
- Article
- Association Between Maternal Protein Intake and the Risk of Adverse Pregnancy Outcomes.Nutrients · 2026Article
- Subtypes of Hypertension 2 to 7 Years After First Pregnancy.Hypertension (Dallas, Tex. : 1979) · 2026Observational
- Multilevel Intersectional Social Drivers of Health and Nulliparous Term, Singleton, Vertex Cesarean Delivery.O&G open · 2026Article
- Racial Differences in Adverse Pregnancy Outcomes and Incident Hypertension: A Mediation Analysis.Journal of the American Heart Association · 2026Article
- Maternal Extracellular Vesicles During Pregnancy and Autism Risk in Children.medRxiv : the preprint server for health sciences · 2026Article
- Endothelial Susceptibility-Related Genetic Variants and Hypertensive Disorders of Pregnancy-Brief Report.Arteriosclerosis, thrombosis, and vascular biology · 2026Article
- Experiences of Discrimination and DNA Methylation Among Black Nulliparous Women.Journal of racial and ethnic health disparities · 2026Article
145 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
22 authors.
Funding
Abstract
objectiveThe primary aim of the "Nulliparous Pregnancy Outcomes Study: monitoring mothers-to-be" is to determine maternal characteristics, which include genetic, physiologic response to pregnancy, and environmental factors that predict adverse pregnancy outcomes. STUDY
designNulliparous women in the first trimester of pregnancy were recruited into an observational cohort study. Participants were seen at 3 study visits during pregnancy and again at delivery. We collected data from in-clinic interviews, take-home surveys, clinical measurements, ultrasound studies, and chart abstractions. Maternal biospecimens (serum, plasma, urine, cervicovaginal fluid) at antepartum study visits and delivery specimens (placenta, umbilical cord, cord blood) were collected, processed, and stored. The primary outcome of the study was defined as pregnancy ending at <37+0 weeks' gestation. Key study hypotheses involve adverse pregnancy outcomes of spontaneous preterm birth, preeclampsia, and fetal growth restriction.
resultsWe recruited 10,037 women to the study. Basic characteristics of the cohort at screening are reported.
conclusionThe "Nulliparous Pregnancy Outcomes Study: monitoring mothers-to-be" cohort study methods and procedures can help investigators when they plan future projects.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.