Trial reportMolecules (Basel, Switzerland)2015
Production and characterization of cosmetic nanoemulsions containing Opuntia ficus-indica (L.) mill extract as moisturizing agent.
Trial report in Molecules (Basel, Switzerland), 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 42 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
42 citing papers in PubMed.
- Low-Molecular-Weight Salmon Collagen Peptides Promote Extracellular Matrix Gene (ECM) Expression in BJ Fibroblasts.International journal of molecular sciences · 2026Article
- Development of nanoemulsion formulation loaded with Enteromorpha intestinalis extract: Characterization and evaluation for topical use.PloS one · 2026Article
- The Beauty Revolution of Nanotechnology: Unveiling the Impact of Cosmetic Nano Wonders.Pharmaceutical nanotechnology · 2026Review
- The Beauty Revolution of Nanotechnology: Unveiling the Impact of Cosmetic Nano Wonders.Pharmaceutical nanotechnology · 2026Review
- Nanoemulsion of Apium graveolens essential oil as a natural pre-emergent herbicide.Scientific reports · 2025Article
- Nanoemulsion ofPharmaceutics · 2025Article
- Hydrogel Biocomposite of Alginate and Mucilage ofACS omega · 2025Article
- Herbal nanoemulsions in cosmetic science: A comprehensive review of design, preparation, formulation, and characterization.Journal of food and drug analysis · 2024Review
- Review
- Encapsulation of Indicaxanthin-RichFoods (Basel, Switzerland) · 2024Article
- Facile Fabrication of Sandalwood Oil-Based Nanoemulsion to Intensify the Fatty Acid Composition in Burned and Rough Skin.ACS omega · 2024Article
- An Updated Review on Nanoemulsion: Factory for Food and Drug Delivery.Current pharmaceutical biotechnology · 2024Review
- A Comparative Study between Onion Peel Extracts, Free and Complexed with β-Cyclodextrin, as a Natural UV Filter to Cosmetic Formulations.International journal of molecular sciences · 2023Article
- Oil-Based Double Emulsion Microcarriers for Enhanced Stability and Bioaccessibility of Betalains and Phenolic Compounds fromFoods (Basel, Switzerland) · 2023Article
- Effect of Banana (Pharmaceutical nanotechnology · 2022Article
- Essential Oil Stabilisation by Response Surface Methodology (RSM): Nanoemulsion Formulation, Physicochemical, Microbiological, and Sensory Investigations.Molecules (Basel, Switzerland) · 2022Article
- Saponins as Natural Emulsifiers for Nanoemulsions.Journal of agricultural and food chemistry · 2022Review
- Development of a novel nanoemulgel formulation containing cumin essential oil as skin permeation enhancer.Drug delivery and translational research · 2022Article
- Beneath the Skin: A Review of Current Trends and Future Prospects of Transdermal Drug Delivery Systems.Pharmaceutics · 2022Review
- Contribution of Nanoscience Research in Antioxidants Delivery Used in Nutricosmetic Sector.Antioxidants (Basel, Switzerland) · 2022Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
This study aimed to produce and characterize an oil in water (O/W) nanoemulsion containing Opuntia ficus-indica (L.) Mill hydroglycolic extract, as well as evaluate its preliminary and accelerated thermal stability and moisturizing efficacy. The formulations containing 0.5% of xanthan gum (FX) and 0.5% of xanthan gum and 1% of Opuntia ficus-indica MILL extract (FXE) were white, homogeneus and fluid in aspect. Both formulations were stable during preliminary and accelerated stability tests. FX and FXE presented a pH compatible to skin pH (4.5-6.0); droplet size varying from 92.2 to 233.6 nm; a polydispersion index (PDI) around 0.200 and a zeta potential from -26.71 to -47.01 mV. FXE was able to increase the water content of the stratum corneum for 5 h after application on the forearm. The O/W nanoemulsions containing 1% of Opuntia ficus-indica (L.) Mill extract presented suitable stability for at least for 60 days. Besides, this formulation was able to increase the water content of stratum corneum, showing its moisturizing efficacy.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.