Evidence map›Paper›PMID 25648436›Full record

ReviewDer Chirurg; Zeitschrift fur alle Gebiete der operativen Medizen2015

[Streptococcal mediastinitis after thyroidectomy. A literature review].

C Bures, V Zielinski, T Klatte, N Swietek, F Kober, E Tatzgern, R Bobak-Wieser, E Gschwandtner, M Gilhofer, A Wechsler-Fördös and 1 more

Abstract readCase ReportsReview
PubMed Publisher
In one paragraph

Review in Der Chirurg; Zeitschrift fur alle Gebiete der operativen Medizen, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed, 1 pooled it
1.7field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 1 synthesis or guideline pooled it, 8 citations in OpenAlex.

  1. [Update of the S2k guidelines : Surgical treatment of benign thyroid diseases].Der Chirurg; Zeitschrift fur alle Gebiete der operativen Medizen · 2018
    Guideline
  2. [Descending necrotizing mediastinitis : Treatment concept with focus on thoracic surgery].Der Chirurg; Zeitschrift fur alle Gebiete der operativen Medizen · 2016
    Article
  3. [Acute and chronic mediastinitis].Der Chirurg; Zeitschrift fur alle Gebiete der operativen Medizen · 2016
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 1 institution in 1 country.

C BuresII. Chirurgische Abteilung "Kaiserin Elisabeth", Krankenanstalt Rudolfstiftung, Wien, Österreich.
V ZielinskiHals-Nasen-Ohren-Abteilung, Krankenanstalt Rudolfstiftung, Wien Juchgasse 25, 1030, Wien, Österreich. valerie.zielinski@wienkav.at.
T KlatteUniversitätsklinik für Urologie, Allgemeines Krankenhaus Wien, Wien, Österreich.
N SwietekUniversitätsklinik für Urologie, Allgemeines Krankenhaus Wien, Wien, Österreich.
F KoberII. Chirurgische Abteilung "Kaiserin Elisabeth", Krankenanstalt Rudolfstiftung, Wien, Österreich.
E TatzgernII. Chirurgische Abteilung "Kaiserin Elisabeth", Krankenanstalt Rudolfstiftung, Wien, Österreich.
R Bobak-WieserII. Chirurgische Abteilung "Kaiserin Elisabeth", Krankenanstalt Rudolfstiftung, Wien, Österreich.
E GschwandtnerII. Chirurgische Abteilung "Kaiserin Elisabeth", Krankenanstalt Rudolfstiftung, Wien, Österreich.
M GilhoferKrankenhaushygiene, Krankenanstalt Rudolfstiftung, Wien, Österreich.
A Wechsler-FördösKrankenhaushygiene, Krankenanstalt Rudolfstiftung, Wien, Österreich.
M HermannII. Chirurgische Abteilung "Kaiserin Elisabeth", Krankenanstalt Rudolfstiftung, Wien, Österreich.
Krankenanstalt Rudolfstiftung der Stadt Wien · AT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionSurgical site infections after thyroid surgery are mostly superficial and can be well treated. Streptococcal mediastinitis in contrast is a rare but life-threatening complication. CASE REPORT: A 57-year-old female patient experienced septic fever, increase of inflammation parameters and erythema 2 days after thyroid surgery for Graves' disease. This process was triggered by a three-compartment infection by group A Streptococcus (GAS) with involvement of the mediastinum. Therapy over 6 weeks including seven wound revisions with the patient under general anesthesia, pathogen-adapted antibiotic treatment and cervical negative pressure treatment managed to control the infection. A total of 21 cases have been published on this phenomenon, 11 of which had a fatal outcome.

conclusionHigh fever and surgical site erythema in the early postoperative period after thyroid surgery can be signs of a GAS infection, which might lead to necrotizing, descending, life-threatening mediastinitis. Early diagnosis with support of computed tomography (CT) scans, immediate therapy including wound opening, lavage, intravenous antibiotic treatment with penicillin and clindamycin are vital. If treatment resistance occurs, cervical negative pressure treatment should be considered.

Indexed as

Streptococcus pyogenesThyroidectomyCombined Modality TherapyFemaleGraves DiseaseHumansMediastinitisMiddle AgedStreptococcal InfectionsSurgical Wound InfectionAntibioticsMediastinitisNegative pressure therapyStreptococcusThyroidectomy

Identifiers

PMID25648436
OpenAlexW15733071

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.