ReviewCytokine2015
Stages versus subsets: Invariant Natural Killer T cell lineage differentiation.
Review in Cytokine, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
14 citing papers in PubMed, 27 citations in OpenAlex.
- Innate-like T Cell Biology in the Tumor Microenvironment Implications for Cancer Immunotherapy.Cells · 2026Review
- Optimizing iNKT-driven immune responses against cancer by modulating CD1d in tumor and antigen presenting cells.Clinical immunology (Orlando, Fla.) · 2024Review
- Traversing the bench to bedside journey for iNKT cell therapies.Frontiers in immunology · 2024Review
- Protein abundance of the cytokine receptor γc controls the thymic generation of innate-like T cells.Cellular and molecular life sciences : CMLS · 2021Article
- miR-183-96-182 Cluster Is Involved in Invariant NKT Cell Development, Maturation, and Effector Function.Journal of immunology (Baltimore, Md. : 1950) · 2019Article
- Quantitative Difference in PLZF Protein Expression Determines iNKT Lineage Fate and Controls Innate CD8 T Cell Generation.Cell reports · 2019Article
- Enhanced oxidative phosphorylation in NKT cells is essential for their survival and function.Proceedings of the National Academy of Sciences of the United States of America · 2019Article
- JNK2 modulates the CD1d-dependent and -independent activation of iNKT cells.European journal of immunology · 2019Article
- Glycoconjugates of Gram-negative bacteria and parasitic protozoa - are they similar in orchestrating the innate immune response?Innate immunity · 2019Review
- Improved Detection of Cytokines Produced by Invariant NKT Cells.Scientific reports · 2017Article
- ATP Binding Cassette Transporter ABCA7 Regulates NKT Cell Development and Function by Controlling CD1d Expression and Lipid Raft Content.Scientific reports · 2017Article
- Article
- NKT10 cells: a novel iNKT cell subset.Oncotarget · 2015Article
- Intravital imaging - dynamic insights into natural killer T cell biology.Frontiers in immunology · 2015Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 2 institutions in 2 countries.
Funding
Abstract
Invariant Natural Killer T (iNKT) cells represent a population of innate T lymphocytes which act as 'first-responders' to infection. While they have long been considered a versatile cell, capable of secretion of multiple cytokines upon activation, recent evidence now indicates that distinct lineages of iNKT cells with unique transcriptional and cytokine profiles exist in different peripheral tissue and as such represent 'fine-tuning' of these cells, which act as mediators between the innate and adaptive immune systems. Here we discuss the molecules regulating the differentiation of iNKT cell lineages, the transcription factors associated with their development, and the role of E protein transcription factors and their negative regulators the Id proteins, as these cells develop from immature progenitor cells to terminally differentiated cells in peripheral tissue.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.