ArticlePediatrics2015
Hair nicotine levels in children with bronchopulmonary dysplasia.
Article in Pediatrics, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.
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Who cites it
22 citing papers in PubMed, 44 citations in OpenAlex.
- Maternal Black Race and Persistent Wheezing Illness in Former Extremely Low Gestational Age Newborns: Secondary Analysis of a Randomized Trial.The Journal of pediatrics · 2018Trial
- Maternal smoking and CC-16: implications for lung development and COPD across the lifespan.American journal of respiratory and critical care medicine · 2026Article
- Long-term pulmonary outcomes in BPD throughout the life-course.Journal of perinatology : official journal of the California Perinatal Association · 2026Review
- Moderate-to-late prematurity: understanding respiratory consequences and modifiable risk factors.European respiratory review : an official journal of the European Respiratory Society · 2025Review
- Parental Report of Indoor Air Pollution Is Associated with Respiratory Morbidities in Bronchopulmonary Dysplasia.The Journal of pediatrics · 2024Article
- Risk factors for poorer respiratory outcomes in adolescents and young adults born preterm.Thorax · 2023Article
- Place-Based Strategies Addressing Neighborhood Environments to Improve Perinatal and Preterm Infant Outcomes.Children (Basel, Switzerland) · 2023Article
- Validation of an outpatient questionnaire for bronchopulmonary dysplasia control.Pediatric pulmonology · 2023Article
- COVID-19 restrictions and hygiene measures reduce the rates of respiratory infections and wheezing among preterm infants.Acta bio-medica : Atenei Parmensis · 2023Article
- Article
- Area deprivation and respiratory morbidities in children with bronchopulmonary dysplasia.Pediatric pulmonology · 2022Article
- Perinatal Inflammatory Biomarkers and Respiratory Disease in Preterm Infants.The Journal of pediatrics · 2022Article
- Insurance coverage and respiratory morbidities in bronchopulmonary dysplasia.Pediatric pulmonology · 2022Article
- Bronchopulmonary dysplasia as a determinant of respiratory outcomes in adult life.Pediatric pulmonology · 2021Article
- Influences of environmental exposures on preterm lung disease.Expert review of respiratory medicine · 2021Review
- Indoor Air Pollution Sources and Respiratory Symptoms in Bronchopulmonary Dysplasia.The Journal of pediatrics · 2020Article
- Impact of road proximity on infants and children with bronchopulmonary dysplasia.Pediatric pulmonology · 2020Article
- Assessing pediatric tobacco exposure using parent report: comparison with hair nicotine.Journal of exposure science & environmental epidemiology · 2018Article
- Respiratory outcomes after initial hospital discharge in children with ventricular shunts and bronchopulmonary dysplasia.Pediatric pulmonology · 2017Article
- The association between environmental tobacco smoke exposure and childhood respiratory disease: a review.Expert review of respiratory medicine · 2017Review
Corrections and comments
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Authors and funding
6 authors at 2 institutions in 1 country.
Funding
Abstract
backgroundTobacco smoke exposure (TSE) may increase respiratory morbidities in young children with bronchopulmonary dysplasia (BPD). Rapid respiratory rates, close proximity to a smoking caregiver, and increased dermal absorption of tobacco smoke components can contribute to systemic exposure. In this study, hair nicotine levels were used as a biomarker of chronic TSE in young children with BPD to determine if hair nicotine levels correlate with caregiver self-report of TSE and respiratory morbidities.
methodsFrom 2012 to 2014, hair nicotine levels were measured from consecutive children seen in a BPD outpatient clinic and compared with caregiver questionnaires on household smoking. The relationship between respiratory morbidities and self-reported TSE or hair nicotine level was assessed.
resultsThe mean hair nicotine level from 117 children was 3.1 ± 13.2 ng/mg. Hair nicotine levels were significantly higher in children from smoking households by caregiver self-report compared with caregivers who reported no smoking (8.2 ± 19.7 ng/mg vs 1.8 ± 10.7; P < .001). In households that reported smoking, hair nicotine levels were higher in children with a primary caregiver who smoked compared with a primary caregiver who did not smoke. Among children with BPD who required respiratory support (n = 50), a significant association was found between higher log hair nicotine levels and increased hospitalizations and limitation of activity.
conclusionsChronic TSE is common in children with BPD, with hair nicotine levels being more likely to detect TSE than caregiver self-report. Hair nicotine levels were also a better predictor of hospitalization and activity limitation in children with BPD who required respiratory support at outpatient presentation.
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Registered trials
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