Evidence map›Paper›PMID 25647284›Full record

Trial reportBlood pressure monitoring2015

Comparison of mercury sphygmomanometry blood pressure readings with oscillometric and central blood pressure in predicting target organ damage in youth.

Elaine M Urbina, Philip R Khoury, Connie E McCoy, Stephen R Daniels, Lawrence M Dolan, Thomas R Kimball

Abstract readClinical TrialComparative Study
In one paragraph

Trial report in Blood pressure monitoring, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
1.5field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 10 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Elaine M UrbinaaCincinnati Children's Hospital Medical Center, University of Cincinnati, Cincinnati, Ohio bDepartment of Pediatrics, University of Colorado, Aurora, Colorado, USA.
Philip R Khoury
Connie E McCoy
Stephen R Daniels
Lawrence M Dolan
Thomas R Kimball
University of Cincinnati · USCincinnati Children's Hospital Medical Center · US

Funding

LCenter for Clinical and Translational Science and TrainingUL1TR001425 · NCATS · UNIVERSITY OF CINCINNATI · PI HEUBI, JAMES E., KISSELA, BRETT M · 2015 to 2024
$37.5M
CTSA INFRASTRUCTURE FOR PEDIATRIC RESEARCHUL1RR026314 · NCRR · UNIVERSITY OF CINCINNATI · PI HEUBI, JAMES E. · 2009 to 2011
$14.3M
Accelerated CV Aging in Youth Related to CV Risk Factor ClustersR01HL105591 · NHLBI · CINCINNATI CHILDRENS HOSP MED CTR · PI URBINA, ELAINE MOTT · 2011 to 2015
$2.7M
CV Disease in Adolescents with Type 2 DiabetesR01HL076269 · NHLBI · CINCINNATI CHILDRENS HOSP MED CTR · PI KIMBALL, THOMAS R · 2005 to 2008
$2.7M
NCATS NIH HHS UL1 TR001425NCRR NIH HHS UL1 RR026314NCRR NIH HHS UL1RR026314NHLBI NIH HHS R01 HL076269NHLBI NIH HHS R01 HL105591
6 · The paper itself

Abstract

objectiveHypertension (HT) is an important risk factor for target organ damage (TOD). New methods for measuring BP are replacing mercury sphygmomanometry in many clinics. We examined the utility of different BP measurement techniques in predicting subclinical TOD in adolescents and young adults.

methodsParticipants in a study of the cardiovascular effects of obesity and type 2 diabetes were evaluated (N=677, 18±3.3 years, 35% male, 60% non-White, 30% with type 2 diabetes). We measured adiposity, laboratory data, left ventricular mass, carotid intima-media thickness, and pulse wave velocity. BP was measured three times by mercury sphygmomanometry (BPm), using an oscillometric device (BPo), and by arterial tonometry to measure central aortic BP (BPc). Participants were stratified as normotensive, prehypertensive, or hypertensive.

resultsThe prevalence of HT in this cohort with a mean BMI of 31 was the highest on BPo measurement (16%), followed by BPm (11%) and BPc (9%; P≤0.001) measurements. BPm was the most consistent in differentiating left ventricular mass and pulse wave velocity among participants in the prehypertensive group as compared with the normotensive and hypertensive groups. Mercury BP measurement was also more sensitive and specific at predicting greater left ventricular mass, pulse wave velocity, and carotid thickness compared with other BP measurement techniques in logistic regression.

conclusionWe conclude that mercury sphygmomanometry should remain the gold standard for evaluation of HT and the risk for TOD in adolescents and young adults.

Indexed as

Blood PressureBlood Pressure MonitorsPulse Wave AnalysisAdolescentAdultAtherosclerosisBlood Pressure Monitoring, AmbulatoryCarotid Intima-Media ThicknessDiabetes Mellitus, Type 2FemaleHumansMaleObesity

Identifiers

PMID25647284
PMCPMC4424141
OpenAlexW2414347047

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.