Evidence map›Paper›PMID 25647058›Full record

ArticleAnnals of surgery2016

Changes of Esophagogastric Junctional Adenocarcinoma and Gastroesophageal Reflux Disease Among Surgical Patients During 1988-2012: A Single-institution, High-volume Experience in China.

Kai Liu, Kun Yang, Weihan Zhang, Xiaolong Chen, Xinzu Chen, Bo Zhang, Zhixin Chen, Jiaping Chen, Yongfan Zhao, Zongguang Zhou and 2 more

2 registry-linked trialsAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Annals of surgery, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 133 papers, 6 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
133citing papers in PubMed, 6 pooled it
5.3field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04710758 narecruitingnot on this mapstarted 2021, after this paper: background citation

Prospective Randomized Controlled Multicenter Clinical Trial For Comparison Of Long-term Outcomes Between Laparoscopic And Open Total Gastrectomy In Patients With Locally Advanced Gastric Cancer

TypeinterventionalSponsorShanghai Zhongshan HospitalRan2021 to 2028Enrolled1,018ConditionsStomach NeoplasmsArmsLaparoscopic total gastrectomy, Open total gastrectomy
NCT06741124 completednot on this mapstarted 2020, after this paper: background citation

Comparison of Channel Esophagogastrostomy and Double Tract Reconstruction After Laparoscopic-assist Proximal Gastrectomy: A Propensity Score-Matched Analysis

TypeobservationalSponsorNorthern Jiangsu People's HospitalRan2020 to 2024Enrolled99ConditionsGastric (Stomach) CancerArmsChannel Esophagogastrostomy, Double Tract Reconstruction
3 · Its place in the literature

Who cites it

133 citing papers in PubMed, 6 syntheses or guidelines pooled it, 186 citations in OpenAlex.

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73 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

12 authors at 2 institutions in 1 country.

Kai Liu*Department of Gastrointestinal Surgery, West China Hospital, Sichuan University, Chengdu, China †Department of Thoracic Surgery, West China Hospital, Sichuan University, Chengdu, China.
Kun Yang
Weihan Zhang
Xiaolong Chen
Xinzu Chen
Bo Zhang
Zhixin Chen
Jiaping Chen
Yongfan Zhao
Zongguang Zhou
Longqi Chen
Jiankun Hu
Sichuan University · CNWest China Hospital of Sichuan University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo evaluate the changes of esophagogastric junctional adenocarcinoma (EGJA) and gastroesophageal reflux disease (GERD) among surgical patients from 1988 to 2012 in a Chinese high-volume hospital.

backgroundThe incidence of EGJA in Western countries has rapidly increased in recent decades. However, recent data from China remain sparse.

methodsA retrospective analysis was performed on the basis of 5053 patients who underwent surgery for gastric and distal esophageal adenocarcinoma. Total of 1723 patients with EGJA who underwent surgery were included. Changes of the prevalence of GERD and the clinicopathological features and surgical treatment of EGJA were longitudinally analyzed by a 5-year interval.

resultsThe proportion of EGJA was increased from 22.3% in period 1 (1988-1992) to 35.7% in period 5 (2008-2012) (P < 0.001). The proportion of Siewert type III (35.9% vs 47.0%) (P < 0.001) and type I (8.7% vs 15.8%) (P = 0.002) tumors of EGJA was also increased during the past 25 years. The prevalence of GERD had increased gradually from 6.5% in period 1 to 10.9% in period 5 for the 3 subgroups without significant difference (P = 0.459). There was an upward tendency with significant difference between the proportion of EGJA and the prevalence of GERD (r = 0.946, P = 0.000). Instead of type II and type III tumors, there was a positive correlation with change in GERD for type I tumors (r = 0.438, P = 0.029). Total gastrectomy was more preferred among patients with EGJA in period 5 than in period 1 (42.0% vs 19.6%) (P < 0.001).

conclusionsAn increasing trend of EGJA is observed during the past 25 years in West China Hospital. The prevalence of GERD among EGJA had showed a gradually increased trend. However, the causality between GERD and EGJA still needs to be researched further. Total gastrectomy is becoming more preferred procedure in patients with EGJA.

Indexed as

Esophagogastric JunctionAdenocarcinomaAdultChinaEsophageal NeoplasmsFemaleGastroesophageal RefluxHospitals, High-VolumeHumansMaleMiddle AgedRetrospective StudiesTime Factors

Identifiers

PMID25647058
PMCPMC4679348
OpenAlexW2327476627

What OpenQuestion holds

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LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.