Evidence map›Paper›PMID 25646954›Full record

ArticlePLoS neglected tropical diseases2015

Describing the breakbone fever: IDODEN, an ontology for dengue fever.

Elvira Mitraka, Pantelis Topalis, Vicky Dritsou, Emmanuel Dialynas, Christos Louis

Abstract read
In one paragraph

Article in PLoS neglected tropical diseases, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

  1. Article
  2. A fourfold pathogen reference ontology suite.Journal of biomedical semantics · 2025
    Article
  3. Article
  4. Article
  5. Review
  6. The Infectious Disease Ontology in the age of COVID-19.Journal of biomedical semantics · 2021
    Article
  7. Article
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Elvira MitrakaInstitute of Molecular Biology and Biotechnology, FORTH, Heraklion, Greece; Department of Biology, University of Crete, Heraklion, Greece.
Pantelis TopalisInstitute of Molecular Biology and Biotechnology, FORTH, Heraklion, Greece.
Vicky DritsouCentre of Functional Genomics, University of Perugia, Perugia, Italy.
Emmanuel DialynasInstitute of Molecular Biology and Biotechnology, FORTH, Heraklion, Greece.
Christos LouisInstitute of Molecular Biology and Biotechnology, FORTH, Heraklion, Greece; Department of Biology, University of Crete, Heraklion, Greece; Centre of Functional Genomics, University of Perugia, Perugia, Italy.

Funding

NIAID NIH HHS HHSN266200400039CNIAID NIH HHS HHSN272200900039CPHS HHS HHSN266200400039CPHS HHS HHSN272200900039C
6 · The paper itself

Abstract

backgroundOntologies represent powerful tools in information technology because they enhance interoperability and facilitate, among other things, the construction of optimized search engines. To address the need to expand the toolbox available for the control and prevention of vector-borne diseases we embarked on the construction of specific ontologies. We present here IDODEN, an ontology that describes dengue fever, one of the globally most important diseases that are transmitted by mosquitoes. METHODOLOGY/PRINCIPAL

findingsWe constructed IDODEN using open source software, and modeled it on IDOMAL, the malaria ontology developed previously. IDODEN covers all aspects of dengue fever, such as disease biology, epidemiology and clinical features. Moreover, it covers all facets of dengue entomology. IDODEN, which is freely available, can now be used for the annotation of dengue-related data and, in addition to its use for modeling, it can be utilized for the construction of other dedicated IT tools such as decision support systems. CONCLUSIONS/SIGNIFICANCE: The availability of the dengue ontology will enable databases hosting dengue-associated data and decision-support systems for that disease to perform most efficiently and to link their own data to those stored in other independent repositories, in an architecture- and software-independent manner.

Indexed as

Biological OntologiesSoftwareAnimalsDatabases, FactualDengueHumans

Identifiers

PMID25646954
PMCPMC4315569

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.