ArticleProceedings of the National Academy of Sciences of the United States of America2015
Auxin binding protein 1 (ABP1) is not required for either auxin signaling or Arabidopsis development.
Article in Proceedings of the National Academy of Sciences of the United States of America, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 173 papers.
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Who cites it
173 citing papers in PubMed, 350 citations in OpenAlex.
- Genomic insights into Serratia bockelmanii strain 201: unlocking its potential for plant growth promotion and salt stress tolerance.BMC microbiology · 2026Article
- Auxin Biosynthesis, Transport, Signaling, and Its Roles in Plant Leaf Morphogenesis.Plants (Basel, Switzerland) · 2025Review
- Mechanisms of auxin action in plant growth and development.Nature reviews. Molecular cell biology · 2025Review
- Harnessing promoter elements to enhance gene editing in plants: perspectives and advances.Plant biotechnology journal · 2025Review
- Dressed Up to the Nines: The Interplay of Phytohormones Signaling and Redox Metabolism During Plant Response to Drought.Plants (Basel, Switzerland) · 2025Review
- Historical and mechanistic perspective on ABP1-TMK1-mediated cell surface auxin signaling.NPJ science of plants · 2025Review
- Prevalence of and gene regulatory constraints on transcriptional adaptation in single cells.Genome biology · 2024Article
- The new horizon of plant auxin signaling via cell-surface co-receptors.Cell research · 2024Article
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- The Mediator Subunit OsMED16 Interacts with the WRKY Transcription Factor OsWRKY45 to Enhance Rice Resistance Against Magnaporthe oryzae.Rice (New York, N.Y.) · 2024Article
- Article
- Discovery of a second-site nia2 mutation in the background of multiple Arabidopsis PIF-related mutants containing the pif3-3 allele.The New phytologist · 2024Article
- Distant cousins come to ABP1's rescue.Science China. Life sciences · 2024Article
- Article
- New Insights into the Enhancement of Adventitious Root Formation Using N,N'-Bis(2,3-methylenedioxyphenyl)urea.Plants (Basel, Switzerland) · 2023Article
- Article
- The First Crested Duck Genome Reveals Clues to Genetic Compensation and Crest Cushion Formation.Genomics, proteomics & bioinformatics · 2023Article
- Phosphorylation and ubiquitination of OsWRKY31 are integral to OsMKK10-2-mediated defense responses in rice.The Plant cell · 2023Article
- Save your TIRs - more to auxin than meets the eye.The New phytologist · 2023Review
113 more citing papers are in PubMed but not listed here.
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Authors and funding
6 authors at 3 institutions in 2 countries.
Funding
Abstract
Auxin binding protein 1 (ABP1) has been studied for decades. It has been suggested that ABP1 functions as an auxin receptor and has an essential role in many developmental processes. Here we present our unexpected findings that ABP1 is neither required for auxin signaling nor necessary for plant development under normal growth conditions. We used our ribozyme-based CRISPR technology to generate an Arabidopsis abp1 mutant that contains a 5-bp deletion in the first exon of ABP1, which resulted in a frameshift and introduction of early stop codons. We also identified a T-DNA insertion abp1 allele that harbors a T-DNA insertion located 27 bp downstream of the ATG start codon in the first exon. We show that the two new abp1 mutants are null alleles. Surprisingly, our new abp1 mutant plants do not display any obvious developmental defects. In fact, the mutant plants are indistinguishable from wild-type plants at every developmental stage analyzed. Furthermore, the abp1 plants are not resistant to exogenous auxin. At the molecular level, we find that the induction of known auxin-regulated genes is similar in both wild-type and abp1 plants in response to auxin treatments. We conclude that ABP1 is not a key component in auxin signaling or Arabidopsis development.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.