ArticleProceedings of the National Academy of Sciences of the United States of America2015
Breakdown of coral colonial form under reduced pH conditions is initiated in polyps and mediated through apoptosis.
Article in Proceedings of the National Academy of Sciences of the United States of America, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.
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Who cites it
18 citing papers in PubMed, 84 citations in OpenAlex.
- Skeleton-Forming Responses of Reef-Building Corals under Ocean Acidification.Research (Washington, D.C.) · 2025Article
- Induction of apoptosis by double-stranded RNA was present in the last common ancestor of cnidarian and bilaterian animals.PLoS pathogens · 2024Article
- The evolution of regulated cell death pathways in animals and their evasion by pathogens.Physiological reviews · 2022Review
- Genetic changes involving the coral gastrovascular system support the transition between colonies and bailed-out polyps: evidence from a Pocillopora acuta transcriptome.BMC genomics · 2021Article
- The history, biological relevance, and potential applications for polyp bailout in corals.Ecology and evolution · 2021Review
- Microscale tracking of coral-vibrio interactions.ISME communications · 2021Article
- Transcriptome Analyses of Immune System Behaviors in Primary Polyp of Coral Acropora digitifera Exposed to the Bacterial Pathogen Vibrio coralliilyticus under Thermal Loading.Marine biotechnology (New York, N.Y.) · 2020Article
- Apoptosis in gonadal somatic cells of scleractinian corals: implications of structural adjustments for gamete production and release.Proceedings. Biological sciences · 2020Article
- The 3D Reconstruction of Pocillopora Colony Sheds Light on the Growth Pattern of This Reef-Building Coral.iScience · 2020Article
- Impact of ocean acidification on crystallographic vital effect of the coral skeleton.Nature communications · 2019Article
- Transcriptome, expression, and activity analyses reveal a vital heat shock protein 70 in the stress response of stony coral Pocillopora damicornis.Cell stress & chaperones · 2018Article
- Epigenome-associated phenotypic acclimatization to ocean acidification in a reef-building coral.Science advances · 2018Article
- The physiological response of the deep-sea coralPeerJ · 2018Article
- Ocean warming and acidification synergistically increase coral mortality.Scientific reports · 2017Article
- Polyp bailout inF1000Research · 2017Article
- The regulation of thermal stress induced apoptosis in corals reveals high similarities in gene expression and function to higher animals.Scientific reports · 2016Article
- Cell proliferation and migration during early development of a symbiotic scleractinian coral.Proceedings. Biological sciences · 2016Article
- A coral-on-a-chip microfluidic platform enabling live-imaging microscopy of reef-building corals.Nature communications · 2016Article
Corrections and comments
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Authors and funding
8 authors at 5 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Certain stony corals can alternate between a calcifying colonial form and noncalcifying solitary polyps, supporting the hypothesis that corals have survived through geologic timescale periods of unfavorable calcification conditions. However, the mechanisms enabling this biological plasticity are yet to be identified. Here we show that incubation of two coral species (Pocillopora damicornis and Oculina patagonica) under reduced pH conditions (pH 7.2) simulating past ocean acidification induce tissue-specific apoptosis that leads to the dissociation of polyps from coenosarcs. This in turn leads to the breakdown of the coenosarc and, as a consequence, to loss of coloniality. Our data show that apoptosis is initiated in the polyps and that once dissociation between polyp and coenosarc terminates, apoptosis subsides. After reexposure of the resulting solitary polyps to normal pH (pH 8.2), both coral species regenerated coenosarc tissues and resumed calcification. These results indicate that regulation of coloniality is under the control of the polyp, the basic modular unit of the colony. A mechanistic explanation for several key evolutionarily important phenomena that occurred throughout coral evolution is proposed, including mechanisms that permitted species to survive the third tier of mass extinctions.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.