Evidence map›Paper›PMID 25646254›Full record

Trial reportThe American journal of tropical medicine and hygiene2015

Engagement of the community, traditional leaders, and public health system in the design and implementation of a large community-based, cluster-randomized trial of umbilical cord care in Zambia.

Davidson H Hamer, Julie M Herlihy, Kebby Musokotwane, Bowen Banda, Chipo Mpamba, Boyd Mwangelwa, Portipher Pilingana, Donald M Thea, Jonathon L Simon, Kojo Yeboah-Antwi and 2 more

Open access · bronzeAbstract readRandomized Controlled Trial
In one paragraph

Trial report in The American journal of tropical medicine and hygiene, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed, 1 pooled it
6.3field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 1 synthesis or guideline pooled it, 28 citations in OpenAlex.

  1. Pooled it
  2. Trial
  3. Trial
  4. Review
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. Article
  17. Article
  18. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 1 institution in 1 country.

Davidson H HamerCenter for Global Health Development, Boston University, Boston, Massachusetts; Department of Global Health, Boston University School of Public Health, Boston, Massachusetts; Zambia Center for Applied Health Research and Development (ZCAHRD), Lusaka, Zambia; Zambia Chlorhexidine Application Trial Field Office, Zambia Center for Applied Health Research and Development (ZCAHRD), Choma, Zambia; Southern Province Medical Office, Choma, Zambia.
Julie M HerlihyCenter for Global Health Development, Boston University, Boston, Massachusetts; Department of Global Health, Boston University School of Public Health, Boston, Massachusetts; Zambia Center for Applied Health Research and Development (ZCAHRD), Lusaka, Zambia; Zambia Chlorhexidine Application Trial Field Office, Zambia Center for Applied Health Research and Development (ZCAHRD), Choma, Zambia; Southern Province Medical Office, Choma, Zambia.
Kebby MusokotwaneCenter for Global Health Development, Boston University, Boston, Massachusetts; Department of Global Health, Boston University School of Public Health, Boston, Massachusetts; Zambia Center for Applied Health Research and Development (ZCAHRD), Lusaka, Zambia; Zambia Chlorhexidine Application Trial Field Office, Zambia Center for Applied Health Research and Development (ZCAHRD), Choma, Zambia; Southern Province Medical Office, Choma, Zambia.
Bowen BandaCenter for Global Health Development, Boston University, Boston, Massachusetts; Department of Global Health, Boston University School of Public Health, Boston, Massachusetts; Zambia Center for Applied Health Research and Development (ZCAHRD), Lusaka, Zambia; Zambia Chlorhexidine Application Trial Field Office, Zambia Center for Applied Health Research and Development (ZCAHRD), Choma, Zambia; Southern Province Medical Office, Choma, Zambia.
Chipo MpambaCenter for Global Health Development, Boston University, Boston, Massachusetts; Department of Global Health, Boston University School of Public Health, Boston, Massachusetts; Zambia Center for Applied Health Research and Development (ZCAHRD), Lusaka, Zambia; Zambia Chlorhexidine Application Trial Field Office, Zambia Center for Applied Health Research and Development (ZCAHRD), Choma, Zambia; Southern Province Medical Office, Choma, Zambia.
Boyd MwangelwaCenter for Global Health Development, Boston University, Boston, Massachusetts; Department of Global Health, Boston University School of Public Health, Boston, Massachusetts; Zambia Center for Applied Health Research and Development (ZCAHRD), Lusaka, Zambia; Zambia Chlorhexidine Application Trial Field Office, Zambia Center for Applied Health Research and Development (ZCAHRD), Choma, Zambia; Southern Province Medical Office, Choma, Zambia.
Portipher PilinganaCenter for Global Health Development, Boston University, Boston, Massachusetts; Department of Global Health, Boston University School of Public Health, Boston, Massachusetts; Zambia Center for Applied Health Research and Development (ZCAHRD), Lusaka, Zambia; Zambia Chlorhexidine Application Trial Field Office, Zambia Center for Applied Health Research and Development (ZCAHRD), Choma, Zambia; Southern Province Medical Office, Choma, Zambia.
Donald M TheaCenter for Global Health Development, Boston University, Boston, Massachusetts; Department of Global Health, Boston University School of Public Health, Boston, Massachusetts; Zambia Center for Applied Health Research and Development (ZCAHRD), Lusaka, Zambia; Zambia Chlorhexidine Application Trial Field Office, Zambia Center for Applied Health Research and Development (ZCAHRD), Choma, Zambia; Southern Province Medical Office, Choma, Zambia.
Jonathon L SimonCenter for Global Health Development, Boston University, Boston, Massachusetts; Department of Global Health, Boston University School of Public Health, Boston, Massachusetts; Zambia Center for Applied Health Research and Development (ZCAHRD), Lusaka, Zambia; Zambia Chlorhexidine Application Trial Field Office, Zambia Center for Applied Health Research and Development (ZCAHRD), Choma, Zambia; Southern Province Medical Office, Choma, Zambia.
Kojo Yeboah-AntwiCenter for Global Health Development, Boston University, Boston, Massachusetts; Department of Global Health, Boston University School of Public Health, Boston, Massachusetts; Zambia Center for Applied Health Research and Development (ZCAHRD), Lusaka, Zambia; Zambia Chlorhexidine Application Trial Field Office, Zambia Center for Applied Health Research and Development (ZCAHRD), Choma, Zambia; Southern Province Medical Office, Choma, Zambia.
Caroline GroganCenter for Global Health Development, Boston University, Boston, Massachusetts; Department of Global Health, Boston University School of Public Health, Boston, Massachusetts; Zambia Center for Applied Health Research and Development (ZCAHRD), Lusaka, Zambia; Zambia Chlorhexidine Application Trial Field Office, Zambia Center for Applied Health Research and Development (ZCAHRD), Choma, Zambia; Southern Province Medical Office, Choma, Zambia.
Katherine E A SemrauCenter for Global Health Development, Boston University, Boston, Massachusetts; Department of Global Health, Boston University School of Public Health, Boston, Massachusetts; Zambia Center for Applied Health Research and Development (ZCAHRD), Lusaka, Zambia; Zambia Chlorhexidine Application Trial Field Office, Zambia Center for Applied Health Research and Development (ZCAHRD), Choma, Zambia; Southern Province Medical Office, Choma, Zambia ksemrau@ariadnelabs.org.
Ministry of Health · ZM

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Conducting research in areas with diverse cultures requires attention to community sensitization and involvement. The process of community engagement is described for a large community-based, cluster-randomized, controlled trial comparing daily 4% chlorhexidine umbilical cord wash to dry cord care for neonatal mortality prevention in Southern Province, Zambia. Study preparations required baseline formative ethnographic research, substantial community sensitization, and engagement with three levels of stakeholders, each necessitating different strategies. Cluster-specific birth notification systems developed with traditional leadership and community members using community-selected data collectors resulted in a post-natal home visit within 48 hours of birth in 96% of births. Of 39,679 pregnant women enrolled (93% of the target of 42,570), only 3.7% were lost to follow-up or withdrew antenatally; 0.2% live-born neonates were lost by day 28 of follow-up. Conducting this trial in close collaboration with traditional, administrative, political, and community stakeholders facilitated excellent study participation, despite structural and sociocultural challenges.

Indexed as

Umbilical CordAdultAnti-Infective Agents, LocalBacterial InfectionsChlorhexidineCommunity ParticipationFemaleHumansInfant, NewbornPostpartum PeriodPregnancyPublic Health AdministrationZambiaAnti-Infective Agents, LocalChlorhexidine

Identifiers

PMID25646254
PMCPMC4350570
OpenAlexW2161442765

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.