Evidence map›Paper›PMID 25646163›Full record

ArticleReceptors & clinical investigation

Regulation of ryanodine receptor-mediated calcium signaling by presenilins.

Andrew J Payne, Simon Kaja, Peter Koulen

Open access · diamondAbstract read
In one paragraph

Article in Receptors & clinical investigation. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
1.7field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 14 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Review
  5. Review
  6. Review
  7. Emerging pathways driving early synaptic pathology in Alzheimer's disease.Biochemical and biophysical research communications · 2017
    Review
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Andrew J PayneVision Research Center, Department of Ophthalmology, University of Missouri - Kansas City, School of Medicine, 2411 Holmes St., Kansas City, MO 64108, USA.
Simon KajaVision Research Center, Department of Ophthalmology, University of Missouri - Kansas City, School of Medicine, 2411 Holmes St., Kansas City, MO 64108, USA.
Peter KoulenVision Research Center, Department of Ophthalmology, University of Missouri - Kansas City, School of Medicine, 2411 Holmes St., Kansas City, MO 64108, USA.
City Vision University · US

Funding

Protein Targets of Oxidative Brain AgingP01AG022550 · NIA · WEST VIRGINIA UNIVERSITY · PI SIMPKINS, JAMES W. · 2003 to 2013
$15.7M
System Gene Delivery for Alzheimer's Disease- SupplementP01AG010485 · NIA · UNIVERSITY OF NORTH TEXAS HLTH SCI CTR · PI ZOLOTUKHIN, SERGEI · 1991 to 2009
$11.3M
ROLE OF MITHOCHONDRIAL ERB IN NEURONAL VULNDERABILITY TO NEUROTOXIC STRESSP01AG027956 · NIA · UNIVERSITY OF NORTH TEXAS HLTH SCI CTR · PI SINGH, MEHARVAN · 2007 to 2017
$11.3M
Mechanisms of calcium signaling in retinal neuronsR01EY014227 · NEI · UNIVERSITY OF NORTH TEXAS HLTH SCI CTR · PI KOULEN, PETER · 2003 to 2006
$1.6M
Novel mechanism of action as therapeutic strategy for optic neuritisR01EY022774 · NEI · UNIVERSITY OF MISSOURI KANSAS CITY · PI KOULEN, PETER · 2012 to 2014
$1.2M
Confocal Laser Scanning MicroscopeS10RR027093 · NCRR · UNIVERSITY OF MISSOURI KANSAS CITY · PI KOULEN, PETER · 2010 to 2010
$497k
CONFOCAL MICROSCOPE FOR CAMPUS EXPANSION IN THE CBH BUILDING: NEUROSCIENCES10RR022570 · NCRR · UNIVERSITY OF NORTH TEXAS HLTH SCI CTR · PI KOULEN, PETER · 2006 to 2006
$356k
NCRR NIH HHS S10 RR022570NCRR NIH HHS S10 RR027093NEI NIH HHS R01 EY014227NEI NIH HHS R01 EY022774NIA NIH HHS P01 AG010485NIA NIH HHS P01 AG022550NIA NIH HHS P01 AG027956
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Identifiers

PMID25646163
PMCPMC4311261
OpenAlexW1544531292

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.