ArticleScientific reports2015
The fate of recent duplicated genes following a fourth-round whole genome duplication in a tetraploid fish, common carp (Cyprinus carpio).
Article in Scientific reports, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 36 papers.
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36 citing papers in PubMed.
- Distinct Evolutionary Trajectories of Major Intracellular Proteolytic Systems in Gilthead Seabream and European Seabass.Biology · 2026Article
- Evolutionary causes and consequences of gene duplication.Nature reviews. Genetics · 2026Review
- Chromosome-level genome assembly of masu salmon (Oncorhynchus masou masou).Scientific data · 2026Article
- Evolutionary diversification and immunoprofiling of cathepsin L toolkit in common carp.Frontiers in cellular and infection microbiology · 2026Article
- Evolutionary Dynamics of Matrix Metalloproteases with Collagenolytic Activity in Teleosts.Animals : an open access journal from MDPI · 2025Article
- Dosage sensitivity shapes balanced expression and gene longevity of homoeologs after whole-genome duplications in angiosperms.The Plant cell · 2024Article
- Decoding the fish genome opens a new era in important trait research and molecular breeding in China.Science China. Life sciences · 2024Review
- Defining autopolyploidy: Cytology, genetics, and taxonomy.American journal of botany · 2024Review
- Expectations of duplicate gene retention under the gene duplicability hypothesis.BMC ecology and evolution · 2023Article
- OAF is a DAF-like gene that controls ovule development in plants.Communications biology · 2023Article
- Dosage balance acts as a time-dependent selective barrier to subfunctionalization.BMC ecology and evolution · 2023Article
- Three amphioxus reference genomes reveal gene and chromosome evolution of chordates.Proceedings of the National Academy of Sciences of the United States of America · 2023Article
- WGDTree: a phylogenetic software tool to examine conditional probabilities of retention following whole genome duplication events.BMC bioinformatics · 2022Article
- A genome-wide comparative evolutionary analysis of zinc finger-BED transcription factor genes in land plants.Scientific reports · 2022Article
- DNA Transposon Expansion is Associated with Genome Size Increase in Mudminnows.Genome biology and evolution · 2021Article
- Parallel subgenome structure and divergent expression evolution of allo-tetraploid common carp and goldfish.Nature genetics · 2021Article
- Evolution of new enzymes by gene duplication and divergence.The FEBS journal · 2020Review
- The round goby genome provides insights into mechanisms that may facilitate biological invasions.BMC biology · 2020Article
- Vertebrate Alpha2,8-Sialyltransferases (ST8Sia): A Teleost Perspective.International journal of molecular sciences · 2020Article
- De novo assembly of the goldfish (Science advances · 2019Article
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9 authors.
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Abstract
Whole genome duplication (WGD) results in extensive genetic redundancy. In plants and yeast, WGD is followed by rapid gene deletions and intense expression differentiation with slow functional divergence. However, the early evolution of the gene differentiation processes is poorly understood in vertebrates because almost all studied WGDs are extremely ancient, and the genomes have returned to a diploid status. Common carp had a very recent fourth round of WGD dated to 8 million years ago. It therefore constitutes an ideal model to study early-stage functional divergence and expression differentiation in vertebrates. We identified 1,757 pairs of recently duplicated genes (RDGs) originating from this specific WGD and found that most ancestral genes were retained in duplicate. Most RDGs were conserved and under selective pressure. Gene expression analysis across six tissues revealed that 92.5% of RDG pairs were co-expressed in at least one tissue and that the expression of nearly half pairs ceased to be strongly correlated, indicating slow spatial divergence but rapid expression dissociation. Functional comparison revealed that 25% of pairs had functional divergence, of which neo- and sub-functionalization were the main outcomes. Our analysis revealed slow gene loss but rapid and intense expression and function differentiation after WGD.
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