Evidence map›Paper›PMID 25645259›Full record

ArticleVirology journal2015

Emergence of human-like H3N2 influenza viruses in pet dogs in Guangxi, China.

Ying Chen, Yan-Ning Mo, Hua-Bo Zhou, Zu-Zhang Wei, Guo-Jun Wang, Qing-Xiong Yu, Xiong Xiao, Wen-Juan Yang, Wei-Jian Huang

Open access · goldAbstract read
In one paragraph

Article in Virology journal, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
1.7field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 24 citations in OpenAlex.

  1. Exposure of dogs to influenza A and B viruses.One health (Amsterdam, Netherlands) · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 2 countries.

Ying ChenCollege of Animal Science and Technology, Guangxi University, No.100 Daxue Road, Nanning, 530004, People's Republic of China. nancychen161@163.com.
Yan-Ning MoCollege of Animal Science and Technology, Guangxi University, No.100 Daxue Road, Nanning, 530004, People's Republic of China. 544032290@qq.com.
Hua-Bo ZhouHuabo Pet Medical Center, Yufeng District, No.342 Liushi Road, Liuzhou, 545005, People's Republic of China. okhbz@yahoo.com.
Zu-Zhang WeiCollege of Animal Science and Technology, Guangxi University, No.100 Daxue Road, Nanning, 530004, People's Republic of China. zuzhangwei@163.com.
Guo-Jun WangDepartment of Microbiology, Mount Sinai School of Medicine, New York, NY, 10029, USA. guojun.wang@mssm.edu.
Qing-Xiong YuCollege of Animal Science and Technology, Guangxi University, No.100 Daxue Road, Nanning, 530004, People's Republic of China. 398267228@qq.com.
Xiong XiaoCollege of Animal Science and Technology, Guangxi University, No.100 Daxue Road, Nanning, 530004, People's Republic of China. 182841043@qq.com.
Wen-Juan YangCollege of Animal Science and Technology, Guangxi University, No.100 Daxue Road, Nanning, 530004, People's Republic of China. 363968194@qq.com.
Wei-Jian HuangCollege of Animal Science and Technology, Guangxi University, No.100 Daxue Road, Nanning, 530004, People's Republic of China. huangweijian-1@163.com.
Guangxi University · CNIcahn School of Medicine at Mount Sinai · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundAfter the 1968 H3N2 pandemic emerged in humans, H3N2 influenza viruses continuously circulated and evolved in nature. An H3N2 variant was circulating in humans in the 1990s and subsequently introduced into the pig population in the 2000s. This virus gradually became the main subtype of swine influenza virus worldwide. However, there were no reports of infections in dogs with this virus.

findingsIn 2013, 35 nasal swabs from pet dogs were positive for Influenza A virus by RT-PCR. Two viruses were isolated and genetically characterized. In the phylogenetic trees of all gene segments, two H3N2 canine isolates clustered with Moscow/10/99 and most H3N2 swine influenza viruses. These results indicated that two H3N2 CIVs possessed high homology with human/swine influenza viruses, which at the same time exhibited some amino acid substitutions in NA, polymerase basic protein 1 (PB1), and nucleoprotein (NP), which probably were related to the interspecies transmission.

conclusionsThese two viruses share the highest homology with swine H3N2, Moscow/99-like viruses, which indicated that these viruses might originate from swine viruses.

Indexed as

AnimalsChinaCluster AnalysisDog DiseasesDogsInfluenza A Virus, H3N2 SubtypeMolecular Sequence DataMutation, MissenseNasal MucosaOrthomyxoviridae InfectionsPetsPhylogenyReverse Transcriptase Polymerase Chain ReactionRNA, ViralSequence Analysis, DNASequence HomologyRNA, ViralViral Proteins

Identifiers

PMID25645259
PMCPMC4324672
OpenAlexW2098590915

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.