Evidence map›Paper›PMID 25645242›Full record

ArticleScandinavian journal of trauma, resuscitation and emergency medicine2015

The epidemiology of do-not-resuscitate orders in patients with trauma: a community level one trauma center observational experience.

Kristin Salottolo, Patrick J Offner, Alessandro Orlando, Denetta S Slone, Charles W Mains, Matthew Carrick, David Bar-Or

Open access · goldAbstract read
In one paragraph

Article in Scandinavian journal of trauma, resuscitation and emergency medicine, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed, 3 pooled it
3.3field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 3 syntheses or guidelines pooled it, 28 citations in OpenAlex.

  1. Pooled it
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  3. Pooled it
  4. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 4 institutions in 1 country.

Kristin SalottoloTrauma Research Department, Swedish Medical Center, Englewood, CO, 80113, USA. ksalottolo@ampiopharma.com.
Patrick J OffnerTrauma Services Department, St. Anthony Hospital, Lakewood, CO, 80228, USA. patrickoffner@centura.org.
Alessandro OrlandoTrauma Research Department, Swedish Medical Center, Englewood, CO, 80113, USA. alessandro.orlando@me.com.
Denetta S SloneTrauma Services Department, Swedish Medical Center, Englewood, CO, 80113, USA. sue.slone@healthonecares.com.
Charles W MainsTrauma Services Department, St. Anthony Hospital, Lakewood, CO, 80228, USA. charleswmains@centura.org.
Matthew CarrickTrauma Services Department, Medical Center of Plano, Plano, TX, 75075, USA. matt.carrick@acutesurgical.com.
David Bar-OrTrauma Research Department, Swedish Medical Center, Englewood, CO, 80113, USA. dbaror@ampiopharma.com.
Swedish Medical Center · USSt. Anthony Hospital · USPlano Cancer Institute · USRocky Vista University · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundDo-Not-Resuscitate (DNR) orders in patients with traumatic injury are insufficiently described. The objective is to describe the epidemiology and outcomes of DNR orders in trauma patients.

methodsWe included all adults with trauma to a community Level I Trauma Center over 6 years (2008-2013). We used chi-square, Wilcoxon rank-sum, and multivariate stepwise logistic regression tests to characterize DNR (established in-house vs. pre-existing), describe predictors of establishing an in-house DNR, timing of an in-house DNR (early [within 1 day] vs late), and outcomes (death, ICU stay, major complications).

resultsIncluded were 10,053 patients with trauma, of which 1523 had a DNR order in place (15%); 715 (7%) had a pre-existing DNR and 808 (8%) had a DNR established in-house. Increases were observed over time in both the proportions of patients with DNRs established in-house (p = 0.008) and age ≥65 (p < 0.001). Over 90% of patients with an in-house DNR were ≥65 years. The following covariates were independently associated with establishing a DNR in-house: age ≥65, severe neurologic deficit (GCS 3-8), fall mechanism of injury, ED tachycardia, female gender, and comorbidities (p < 0.05 for all). Age ≥65, female gender, non-surgical service admission and transfers-in were associated with a DNR established early (p < 0.05 for all). As expected, mortality was greater in patients with DNR than those without (22% vs. 1%), as was the development of a major complication (8% vs. 5%), while ICU admission was similar (19% vs. 17%). Poor outcomes were greatest in patients with DNR orders executed later in the hospital stay.

conclusionsOur analysis of a broad cohort of patients with traumatic injury establishes the relationship between DNR and patient characteristics and outcomes. At 15%, DNR orders are prevalent in our general trauma population, particularly in patients ≥65 years, and are placed early after arrival. Established prognostic factors, including age and physiologic severity, were determinants for in-house DNR orders. These data may improve physician predictions of outcomes with DNR and help inform patient preferences, particularly in an environment with increasing use of DNR and increasing age of patients with trauma.

Indexed as

Resuscitation OrdersAdultAgedAge FactorsComorbidityFemaleGlasgow Coma ScaleHospital MortalityHumansMaleMiddle AgedSex FactorsTime FactorsTrauma CentersWounds and Injuries

Identifiers

PMID25645242
PMCPMC4333154
OpenAlexW2072753309

What OpenQuestion holds

Textmetadata
LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.