Observational studyThe American journal of cardiology2015
Usefulness of cognitive dysfunction in heart failure to predict cardiovascular risk at 180 days.
Observational study in The American journal of cardiology, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
24 citing papers in PubMed, 1 synthesis or guideline pooled it, 31 citations in OpenAlex.
- Brain Imaging Changes and Related Risk Factors of Cognitive Impairment in Patients With Heart Failure.Frontiers in cardiovascular medicine · 2021Pooled it
- Prospective randomized clinical trial on comprehensive cardiac rehabilitation combined with individualized cognitive training in older adults with heart failure and mild cognitive impairment.American heart journal plus : cardiology research and practice · 2026Article
- Cognitive assessment in heart failure: clinical value, timing, and practical tools.Heart failure reviews · 2026Review
- Exploring the Relationship Between Sleep Disturbances, Gut Microbiota, and Cognition in Patients with Heart Failure: A Cross-Sectional Study.Medicina (Kaunas, Lithuania) · 2026Article
- Fatigue and Cognitive Impairment in Patients with Kidney Failure Not Requiring Kidney Replacement Therapy and Patients Receiving Hemodialysis: A Cross-Sectional Study.Brain sciences · 2026Article
- Indication for durable mechanical circulatory support: an expert opinion review.ESC heart failure · 2026Review
- The association between frailty status and cognitive function in patients with cardiovascular diseases: a nationwide cohort study.Scientific reports · 2025Article
- Scoping review of the use of multimorbidity variables in cardiovascular disease risk prediction.BMC public health · 2025Article
- Geriatric Vulnerabilities Among Adults With Heart Failure With Preserved Ejection Fraction: A Cross-Continent Evaluation.JACC. Advances · 2025Article
- Linking the heart and brain in type 2 diabetes: association between global longitudinal strain and cognitive function.Frontiers in endocrinology · 2025Article
- Cognitive decline assessed using a brief screening test and cardiovascular and non-cardiovascular events in older patients with heart failure.Aging clinical and experimental research · 2023Article
- Malnutrition in heart failure with preserved ejection fraction.Journal of the American Geriatrics Society · 2023Article
- Geriatric Domains in Patients with Heart Failure with Preserved Ejection Fraction.Cardiology clinics · 2022Review
- Exercise and Cognitive Training Intervention Improves Self-Care, Quality of Life and Functional Capacity in Persons With Heart Failure.Journal of applied gerontology : the official journal of the Southern Gerontological Society · 2022Article
- Performances on the Montreal Cognitive Assessment Along the Cardiovascular Disease Continuum.Archives of clinical neuropsychology : the official journal of the National Academy of Neuropsychologists · 2022Article
- Cognitive Impairment in Acute Heart Failure: Narrative Review.Journal of cardiovascular development and disease · 2021Review
- Cognitive impairment associated with increased mortality rate in patients with heart failure: A systematic review and meta-analysis.Journal of the Saudi Heart Association · 2019Article
- Heart Failure and Cognitive Impairment: Clinical Relevance and Therapeutic Considerations.Current cardiology reviews · 2019Review
- Combined Influence of Depression and Physical Frailty on Cognitive Impairment in Patients with Heart Failure.International journal of environmental research and public health · 2018Article
- Cognitive Deficit in Heart Failure and the Benefits of Aerobic Physical Activity.Arquivos brasileiros de cardiologia · 2018Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 1 institution in 1 country.
Funding
Abstract
Cognitive dysfunction is common in patients with heart failure (HF). Despite the high prevalence and the adverse associations of cognitive dysfunction in HF, the prognostic implications remain poorly understood. We sought to determine the influence of cognitive dysfunction, identified using the Montreal Cognitive Assessment (MoCA), on 180-day cardiovascular events. We analyzed data on 246 participants in an observational cohort study of adults with HF. The interview-format MoCA was administered to all participants. Time to first cardiovascular event was assessed as a cumulative end point during the 180 days after enrollment. Cox proportional hazards model was used for analysis of time to first event. The MoCA score was <26 for 91 patients (37%). Patients with a MoCA score <26 were more likely to have a cardiovascular event at 180 days. MoCA score <26 remained an independent predictor of cardiovascular event risk at 180 days when adjusted for the Seattle Heart Failure Model Score and the Charlson comorbidity index (hazard ratio 1.7, 95% confidence interval 1.1 to 2.6, p = 0.03). In conclusion, in patients with HF, cognitive dysfunction identified with a MoCA score of <26 is associated with increased risk of cardiovascular events at 180 days.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.