Evidence map›Paper›PMID 25644816›Full record

ReviewCurrent diabetes reports2015

Preeclampsia and diabetes.

Tracey L Weissgerber, Lanay M Mudd

Open access · greenAbstract readReview
In one paragraph

Review in Current diabetes reports, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 158 papers, 9 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
158citing papers in PubMed, 9 pooled it
12.2field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

158 citing papers in PubMed, 9 syntheses or guidelines pooled it, 353 citations in OpenAlex.

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  9. Evaluation of Preeclampsia Results after Use of Metformin in Gestation: Systematic Review and Meta-analysis.Revista brasileira de ginecologia e obstetricia : revista da Federacao Brasileira das Sociedades de Ginecologia e Obstetricia · 2018
    Pooled it
  10. Article
  11. The pathophysiology of pre-eclampsia.Nature reviews. Nephrology · 2026
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98 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 2 institutions in 1 country.

Tracey L WeissgerberDivision of Nephrology and Hypertension, Mayo Clinic, 200 1st St. SW, RO-HA-06-675B-5, Rochester, MN, 55905, USA, weissgerber.tracey@mayo.edu.
Lanay M Mudd
Michigan State University · USWinnMed · US

Funding

Rochester Epidemiology ProjectR01AG034676 · NIA · MAYO CLINIC ROCHESTER · PI ROCCA, WALTER A, ST SAUVER, JENNIFER LYNN · 2010 to 2019
$9.5M
Mayo Clinic Interdisciplinary Women's Health Research ProgramK12HD065987 · NICHD · MAYO CLINIC ROCHESTER · PI KANTARCI, KEJAL · 2010 to 2023
$6.7M
Building Interdisciplinary Research Careers in Women's Health at Michigan StateK12HD065879 · NICHD · MICHIGAN STATE UNIVERSITY · PI HOLZMAN, CLAUDIA B. · 2010 to 2014
$2.5M
NIA NIH HHS R01 AG034676NICHD NIH HHS K12 HD065879NICHD NIH HHS K12HD065879-03NICHD NIH HHS K12 HD065987NICHD NIH HHS K12HD065987
6 · The paper itself

Abstract

Preeclampsia is diagnosed in women presenting with new onset hypertension accompanied by proteinuria or other signs of severe organ dysfunction in the second half of pregnancy. Preeclampsia risk is increased 2- to 4-fold among women with type 1 or type 2 diabetes. The limited number of pregnant women with preexisting diabetes and the difficulties associated with diagnosing preeclampsia in women with proteinuria prior to pregnancy are significant barriers to research in this high-risk population. Gestational diabetes mellitus (GDM) also increases preeclampsia risk, although it is unclear whether these two conditions share a common pathophysiological pathway. Nondiabetic women who have had preeclampsia are more likely to develop type 2 diabetes later in life. Among women with type 1 diabetes, a history of preeclampsia is associated with an increased risk of retinopathy and nephropathy. More research examining the pathophysiology, treatment, and the long-term health implications of preeclampsia among women with preexisting and gestational diabetes is needed.

Indexed as

Diabetes, GestationalDiabetes Mellitus, Type 1Diabetes Mellitus, Type 2FemaleHumansPre-EclampsiaPregnancyRisk Factors

Identifiers

PMID25644816
PMCPMC4317712
OpenAlexW1992568131

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.