Evidence map›Paper›PMID 25644711›Full record

ArticleObesity (Silver Spring, Md.)2015

Chocolate-candy consumption and 3-year weight gain among postmenopausal U.S. women.

James A Greenberg, JoAnn E Manson, Brian Buijsse, Lu Wang, Matthew A Allison, Marian L Neuhouser, Lesley Tinker, Molly E Waring, Carmen R Isasi, Lisa W Martin and 1 more

Abstract read
In one paragraph

Article in Obesity (Silver Spring, Md.), 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed, 4 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 4 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. Pooled it
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Effects of Cocoa Antioxidants in Type 2 Diabetes Mellitus.Antioxidants (Basel, Switzerland) · 2017
    Review
  12. Homeostatic theory of obesity.Health psychology open · 2015
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

James A GreenbergBrooklyn College of the City University of New York, Brooklyn, New York, USA.
JoAnn E Manson
Brian Buijsse
Lu Wang
Matthew A Allison
Marian L Neuhouser
Lesley Tinker
Molly E Waring
Carmen R Isasi
Lisa W Martin
Cynthia A Thomson

Funding

Stable Isotope and Metabolomics CoreP60DK020541 · NIDDK · YESHIVA UNIVERSITY · PI FLEISCHER, NORMAN S. · 1986 to 2014
$29.8M
Translational Research CoreP30DK020541 · NIDDK · ALBERT EINSTEIN COLLEGE OF MEDICINE, INC · PI JEFFREY E. PESSIN · 2015 to 2026
$27.7M
TRACE-COREU01HL105268 · NHLBI · UNIV OF MASSACHUSETTS MED SCH WORCESTER · PI KIEFE, CATARINA I. · 2010 to 2013
$5.8M
University of Massachusetts Center for Clinical and Translational ScienceKL2TR000160 · NCATS · UNIV OF MASSACHUSETTS MED SCH WORCESTER · PI LUZURIAGA, KATHERINE F · 2012 to 2014
$1.7M
Vitamin D Status, Vitamin D Receptor Gene Variants, and Hypertension RiskR00HL095649 · NHLBI · BRIGHAM AND WOMEN'S HOSPITAL · PI WANG, LU · 2012 to 2014
$729k
VANGUARD CENTER FOR WOMEN'S HEALTH INITIATIVEN01WH032109 · WH · BRIGHAM AND WOMEN'S HOSPITAL · PI MANSON, JOANN ELISABETH · 1993 to 2000
$401k
Vitamin D Status, Vitamin D Receptor Gene Variants, and Hypertension RiskK99HL095649 · NHLBI · BRIGHAM AND WOMEN'S HOSPITAL · PI WANG, LU · 2010 to 2011
$179k
NCATS NIH HHS KL2 TR000160NCATS NIH HHS KL2TR000160NHLBI NIH HHS HHSN268201100001INHLBI NIH HHS HHSN268201100003INHLBI NIH HHS HHSN268201100004INHLBI NIH HHS HHSN268201100046CNHLBI NIH HHS K99 HL095649NHLBI NIH HHS R00 HL095649NHLBI NIH HHS U01 HL105268NIA NIH HHS HHSN271201100004CNIDDK NIH HHS P30 DK020541NIDDK NIH HHS P60 DK020541WHI NIH HHS HHSN268201100001CWHI NIH HHS HHSN268201100003CWHI NIH HHS HHSN268201100004CWHI NIH HHS N01 WH032109
6 · The paper itself

Abstract

objectiveTo test the hypothesis that greater chocolate-candy intake is associated with more weight gain in postmenopausal women.

methodsA prospective cohort study involved 107,243 postmenopausal American women aged 50-79 years (mean = 60.7) at enrollment in the Women's Health Initiative, with 3-year follow-up. Chocolate-candy consumption was assessed by food frequency questionnaire, and body weight was measured. Linear mixed models, adjusted for demographic, socio economic, anthropomorphic, and behavioral variables, were used to test our main hypotheses.

resultsCompared with women who ate a 1 oz (∼28 g) serving of chocolate candy <1 per month, those who ate this amount 1 per month to <1 per week, 1 per week to < 3 per week and ≥3 per week showed greater 3-year prospective weight gains (kg) of 0.76 (95% CI: 0.66, 0.85), 0.95 (0.84, 1.06), and 1.40 (1.27, 1.53), respectively, (P for linear trend<0.0001). Each additional 1 oz/day was associated with a greater 3-year weight gain (kg) of 0.92 (0.80, 1.05). The weight gain in each chocolate-candy intake level increased as BMI increased above the normal range (18.5-25 kg/m(2)), and was inversely associated with age.

conclusionsGreater chocolate-candy intake was associated with greater prospective weight gain in this cohort of postmenopausal women.

Indexed as

CacaoCandyFeeding BehaviorWeight GainAgedBody WeightFemaleFollow-Up StudiesHumansMiddle AgedOverweightPostmenopauseProspective StudiesSurveys and QuestionnairesUnited States

Identifiers

PMID25644711
PMCPMC4351742

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.