Evidence map›Paper›PMID 25644701›Full record

ArticleGenetics2015

Complex formation of RNA silencing proteins in the perinuclear region of Neurospora crassa.

Logan M Decker, Erin C Boone, Hua Xiao, Benjamin S Shanker, Shannon F Boone, Shanika L Kingston, Seung A Lee, Thomas M Hammond, Patrick K T Shiu

Open access · bronzeAbstract read
In one paragraph

Article in Genetics, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
1.8field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 25 citations in OpenAlex.

  1. Article
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  8. The Evolutionary Significance of RNAi in the Fungal Kingdom.International journal of molecular sciences · 2020
    Review
  9. Article
  10. Article
  11. Article
  12. Article
  13. Review
  14. Article
  15. Article
  16. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 1 country.

Logan M DeckerDivision of Biological Sciences, University of Missouri, Columbia, Missouri 65211.
Erin C BooneDivision of Biological Sciences, University of Missouri, Columbia, Missouri 65211.
Hua XiaoDivision of Biological Sciences, University of Missouri, Columbia, Missouri 65211.
Benjamin S ShankerDivision of Biological Sciences, University of Missouri, Columbia, Missouri 65211.
Shannon F BooneDivision of Biological Sciences, University of Missouri, Columbia, Missouri 65211.
Shanika L KingstonDepartment of Biology, Barry University, Miami Shores, Florida 33161.
Seung A LeeDivision of Biological Sciences, University of Missouri, Columbia, Missouri 65211.
Thomas M HammondSchool of Biological Sciences, Illinois State University, Normal, Illinois, 61790.
Patrick K T ShiuDivision of Biological Sciences, University of Missouri, Columbia, Missouri 65211 shiup@missouri.edu.
University of Missouri · USBarry University · USIllinois State University · US

Funding

Tools for Functional Analysis and Cell BiologyP01GM068087 · NIGMS · DARTMOUTH COLLEGE · PI DUNLAP, JAY C. · 2004 to 2013
$19.3M
BIOMEDICAL RESEARCH AT BARRY UNIVERSITYR25GM059244 · NIGMS · BARRY UNIVERSITY · PI REDWAY, FLONA ARUNDEL · 2001 to 2017
$4.0M
NIGMS NIH HHS P01 GM068087NIGMS NIH HHS R25 GM059244
6 · The paper itself

Abstract

In Neurospora, genes not paired during meiosis are targeted by meiotic silencing by unpaired DNA (MSUD). Here, our bimolecular fluorescence complementation (BiFC) study suggests that RNA-directed RNA polymerase, Dicer, Argonaute, and others form a silencing complex in the perinuclear region, with intimate interactions among the majority of them. We have also shown that SAD-2 is likely the anchor for this assembly.

Indexed as

Gene SilencingArgonaute ProteinsFungal ProteinsKaryopherinsNeurospora crassaProtein BindingProtein TransportRibonuclease IIIArgonaute ProteinsFungal ProteinsKaryopherinsRibonuclease IIIbimolecular fluorescence complementation (BiFC)fluorescent protein taggingmeiotic silencing by unpaired DNA (MSUD)Neurospora crassaRNA interference

Identifiers

PMID25644701
PMCPMC4391574
OpenAlexW2122875275

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.