ArticleThe journal of physiological sciences : JPS2015
Computational analysis of the effect of valvular regurgitation on ventricular mechanics using a 3D electromechanics model.
Article in The journal of physiological sciences : JPS, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.
What it found
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The trial behind it
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Who cites it
15 citing papers in PubMed, 21 citations in OpenAlex.
- Transmural Distribution of Coronary Perfusion and Myocardial Work Density Due to Alterations in Ventricular Loading, Geometry and Contractility.Frontiers in physiology · 2021Article
- Prediction of Cardiac Mechanical Performance From Electrical Features During Ventricular Tachyarrhythmia Simulation Using Machine Learning Algorithms.Frontiers in physiology · 2020Article
- Effect of myocardial heterogeneity on ventricular electro-mechanical responses: a computational study.Biomedical engineering online · 2019Article
- Intra-aortic balloon pump postcardiac surgery: A literature review.Journal of research in medical sciences : the official journal of Isfahan University of Medical Sciences · 2019Review
- Computational analysis of the electromechanical performance of mitral valve cerclage annuloplasty using a patient-specific ventricular model.The Korean journal of physiology & pharmacology : official journal of the Korean Physiological Society and the Korean Society of Pharmacology · 2019Article
- The effect of myocardial action potential duration on cardiac pumping efficacy: a computational study.Biomedical engineering online · 2018Article
- Effect of KCNQ1 G229D mutation on cardiac pumping efficacy and reentrant dynamics in ventricles: Computational study.International journal for numerical methods in biomedical engineering · 2018Article
- Computational prediction of the effects of the intra-aortic balloon pump on heart failure with valvular regurgitation using a 3D cardiac electromechanical model.Medical & biological engineering & computing · 2018Article
- Computational analysis of the effect of mitral and aortic regurgitation on the function of ventricular assist devices using 3D cardiac electromechanical model.Medical & biological engineering & computing · 2018Article
- Influence of the KCNQ1 S140G Mutation on Human Ventricular Arrhythmogenesis and Pumping Performance: Simulation Study.Frontiers in physiology · 2018Article
- The effect of electrical conductivity of myocardium on cardiac pumping efficacy: a computational study.Biomedical engineering online · 2017Article
- How computer simulations of the human heart can improve anti-arrhythmia therapy.The Journal of physiology · 2016Review
- Mechanisms of astrocytic K(+) clearance and swelling under high extracellular K(+) concentrations.The journal of physiological sciences : JPS · 2016Article
- Mathematical analysis of the effects of valvular regurgitation on the pumping efficacy of continuous and pulsatile left ventricular assist devices.Integrative medicine research · 2016Article
- A New MRI-Based Model of Heart Function with Coupled Hemodynamics and Application to Normal and Diseased Canine Left Ventricles.Frontiers in bioengineering and biotechnology · 2015Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 4 institutions in 2 countries.
Funding
Abstract
Using a three-dimensional electromechanical model of the canine ventricles with dyssynchronous heart failure, we investigated the relationship between severity of valve regurgitation and ventricular mechanical responses. The results demonstrated that end-systolic tension in the septum and left ventricular free wall was significantly lower under the condition of mitral regurgitation (MR) than under aortic regurgitation (AR). Stroke work in AR was higher than that in MR. On the other hand, the difference in stroke volume between the two conditions was not significant, indicating that AR may cause worse pumping efficiency than MR in terms of consumed energy and performed work.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.