Evidence map›Paper›PMID 25644333›Full record

ArticleThe American journal of case reports2015

Thyroid storm caused by a chinese herb contaminated with thyroid hormones.

Maude St-Onge, Hilde Vandenberghe, Margaret Thompson

Open access · hybridAbstract readCase Reports
In one paragraph

Article in The American journal of case reports, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
1.4field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 4 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Maude St-OngeDepartment of Clinical Pharmacology and Toxicology, Fellow for the Ontario & Manitoba Poison Centre, University of Toronto, Intensivist Clinical Associate for the Department of Critical Care Medicine at the Sunnybrook Health Sciences Centre, Toronto, ON, Canada.
Hilde VandenbergheDepartment of Laboratory Medicine, St. Michael Hospital, Toronto, ON, Canada.
Margaret ThompsonOntario & Manitoba Poison Centre, Program Director of the Clinical Pharmacology and Toxicology program at the University of Toronto, University of Toronto, Toronto, ON, Canada.
Sunnybrook Health Science Centre · CA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundWe report a case of thyroid storm caused by consuming a Chinese herb contaminated with thyroid hormones. CASE REPORT: A 70-year-old man presented to an emergency department after 2 days of nausea, vomiting, and weakness. Three days previously, he had started taking Cordyceps powder and "Flower Man Sang Hung" as recommended by his Chinese physician. Following admission, the patient deteriorated and was eventually diagnosed with thyroid storm complicated by rapid atrial fibrillation requiring cardioversion, intubation, and intensive care admission. The analysis of the Chinese herb "Flower Man Sang Hung" was positive for levothyroxine. The patient was extubated 11 days after admission and discharged to a rehabilitation centre after 17 days of hospitalization. The Chinese medicine physician was informed of the events.

conclusionsHerbal products can be the source of illness, medication interactions, and contamination. Awareness should be raised among Chinese medicine physicians, allopathic physicians, and their patients. Clinicians should also have a low threshold of suspicion to seek laboratory analysis of suspect substances when the cause of the clinical presentation is unclear.

Indexed as

AgedDrug CombinationsDrugs, Chinese HerbalHumansMaleThyroid CrisisThyroid HormonesThyroxineDrug CombinationsDrugs, Chinese HerbalThyroid HormonesThyroxine

Identifiers

PMID25644333
PMCPMC4321408
OpenAlexW2112026342

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.