Evidence map›Paper›PMID 25644056›Full record

ArticleInternational journal of obesity (2005)2015

Maternal and neonatal outcomes for pregnancies before and after gastric bypass surgery.

T D Adams, A O Hammoud, L E Davidson, B Laferrère, A Fraser, J B Stanford, M Hashibe, J L J Greenwood, J Kim, D Taylor and 6 more

Open access · greenAbstract read
In one paragraph

Article in International journal of obesity (2005), 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 30 papers, 5 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
30citing papers in PubMed, 5 pooled it
23.9field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

30 citing papers in PubMed, 5 syntheses or guidelines pooled it, 126 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. Pooled it
  5. Pooled it
  6. Article
  7. Review
  8. Pathophysiology of Maternal Obesity and Hypertension in Pregnancy.Journal of cardiovascular development and disease · 2025
    Review
  9. Review
  10. Observational
  11. Article
  12. Review
  13. Maternal and fetal outcomes after bariatric surgeries.Przeglad menopauzalny = Menopause review · 2023
    Article
  14. Familial aggregation of stillbirth: A pedigree analysis of a matched case-control study.BJOG : an international journal of obstetrics and gynaecology · 2023
    Article
  15. Article
  16. Review
  17. Article
  18. Review
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors at 5 institutions in 1 country.

T D AdamsDivision of Cardiovascular Genetics, University of Utah and LiVe Well Center Salt Lake, Intermountain Healthcare, Salt Lake City, UT, USA.
A O Hammoud1] VF Michigan, Bloomfield Hills, MI, USA [2] Department of Obstetrics and Gynecology, University of Utah, Salt Lake City, UT, USA.
L E Davidson1] Department of Exercise Science, Brigham Young University, Provo, UT, USA [2] Division of Cardiovascular Genetics, University of Utah, Salt Lake City, UT, USA.
B LaferrèreSt Luke's Roosevelt Hospital Center, Columbia University College of Physicians and Surgeons and New York Obesity Nutrition Research Center, Division of Endocrinology, Diabetes and Nutrition, New York, NY, USA.
A FraserDepartment of Population Sciences, Huntsman Cancer Institute, University of Utah, Salt Lake City, UT, USA.
J B StanfordDivision of Public Health, University of Utah, Salt Lake City, UT, USA.
M HashibeDivision of Public Health, University of Utah, Salt Lake City, UT, USA.
J L J GreenwoodDivision of Public Health, University of Utah, Salt Lake City, UT, USA.
J KimDivision of Public Health, University of Utah, Salt Lake City, UT, USA.
D TaylorHomer Warner Center for Informatics Research, Intermountain Healthcare, Salt Lake City, UT, USA.
A J WatsonDepartment of Obstetrics and Gynecology, University of Utah, Salt Lake City, UT, USA.
K R SmithDepartment of Population Sciences, Huntsman Cancer Institute and Department of Family and Consumer Studies, University of Utah, Salt Lake City, UT, USA.
R McKinlayRocky Mountain Associated Physicians, Inc., Salt Lake City, UT, USA.
S C SimperRocky Mountain Associated Physicians, Inc., Salt Lake City, UT, USA.
S C SmithRocky Mountain Associated Physicians, Inc., Salt Lake City, UT, USA.
S C HuntDivision of Cardiovascular Genetics, University of Utah, Salt Lake City, UT, USA.
University of Utah · USIntermountain Healthcare · USBrigham Young University · USCranbrook Academy of Art · USSt. Luke's-Roosevelt Hospital Center · US

Funding

VIRAL DAMAGE TO BRAIN AND NEUROMUSCULAR SYSTEMM01RR000064 · NCRR · UNIVERSITY OF UTAH · PI SWOBODA, KATHRYN J. · 1985 to 2008
$21.7M
University of Utah Center for Clinical and Translational ScienceUL1TR001067 · NCATS · UNIVERSITY OF UTAH · PI DERE, WILLARD H., HESS, RACHEL · 2013 to 2017
$19.8M
The Utah Study of Fertility, Longevity and AgingR01AG022095 · NIA · UNIVERSITY OF UTAH · PI SMITH, KEN R · 2003 to 2015
$9.4M
MORBIDITY/MORTALITY RELATED TO GASTRIC BYPASS SURGERYR01DK055006 · NIDDK · UNIVERSITY OF UTAH · PI HOPKINS, PAUL N · 2000 to 2014
$7.8M
Mechanisms of Diabetes Control After Weight Loss SurgeryR01DK067561 · NIDDK · ST. LUKE'S-ROOSEVELT INST FOR HLTH SCIS · PI LAFERRERE, BLANDINE B · 2005 to 2013
$3.1M
University of Utah Center for clinical and Translational ScienceKL2TR001065 · NCATS · UNIVERSITY OF UTAH · PI DERE, WILLARD H., HESS, RACHEL · 2013 to 2017
$1.1M
NCATS NIH HHS KL2 TR001065NCATS NIH HHS UL1 TR001067NCRR NIH HHS M01 RR000064NCRR NIH HHS M01-RR00064NIA NIH HHS R01 AG022095NIA NIH HHS R01-AG-022095NIDDK NIH HHS R01 DK055006NIDDK NIH HHS R01 DK067561NIDDK NIH HHS R01-DK-55006
6 · The paper itself

Abstract

backgroundInteraction between maternal obesity, intrauterine environment and adverse clinical outcomes of newborns has been described.

methodsUsing statewide birth certificate data, this retrospective, matched-control cohort study compared paired birth weights and complications of infants born to women before and after Roux-en-Y gastric bypass surgery (RYGB) and to matched obese non-operated women in several different groups. Women who had given birth to a child before and after RYGB (group 1; n=295 matches) and women with pregnancies after RYGB (group 2; n=764 matches) were matched to non-operated women based on age, body mass index (BMI) prior to both pregnancy and RYGB, mother's race, year of mother/s birth, date of infant births and birth order. In addition, birth weights of 13 143 live births before and/or after RYGB of their mothers (n=5819) were compared (group 3).

resultsOdds ratios (ORs) for having a large-for-gestational-age (LGA) neonate were significantly less after RYGB than for non-surgical mothers: ORs for groups 1 and 2 were 0.19 (0.08-0.38) and 0.33 (0.21-0.51), respectively. In contrast, ORs in all three groups for risk of having a small for gestational age (SGA) neonate were greater for RYGB mothers compared to non-surgical mothers (ORs were 2.16 (1.00-5.04); 2.16 (1.43-3.32); and 2.25 (1.89-2.69), respectively). Neonatal complications were not different for group 1 RYGB and non-surgical women for the first pregnancy following RYGB. Pregnancy-induced hypertension and gestational diabetes were significantly lower for the first pregnancy of mothers following RYGB compared to matched pregnancies of non-surgical mothers.

conclusionWomen who had undergone RYGB not only had lower risk for having an LGA neonate compared to BMI-matched mothers, but also had significantly higher risk for delivering an SGA neonate following RYGB. RYGB women were less likely than non-operated women to have pregnancy-related hypertension and diabetes.

Indexed as

Gastric BypassMothersAdultBirth WeightFemaleHumansInfantInfant, NewbornMaleObesity, MorbidOdds RatioPregnancyPregnancy ComplicationsPregnancy OutcomeRetrospective StudiesUnited States

Identifiers

PMID25644056
PMCPMC5209789
OpenAlexW2058686283

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.