Evidence map›Paper›PMID 25643217›Full record

ArticleNeuropsychology2015

Cognitive factors contributing to spelling performance in children with prenatal alcohol exposure.

Leila Glass, Diana M Graham, Natacha Akshoomoff, Sarah N Mattson

Open access · hybridAbstract read
In one paragraph

Article in Neuropsychology, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed, 2 pooled it
2.3field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 2 syntheses or guidelines pooled it, 18 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Article
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  6. Review
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  9. Review
  10. Review
  11. Fetal Alcohol Spectrum Disorders: A Case Study.Journal of pediatric neuropsychology · 2017
    Article
  12. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Leila GlassCenter for Behavioral Teratology.
Diana M GrahamCenter for Behavioral Teratology.
Natacha AkshoomoffDepartment of Psychiatry.
Sarah N MattsonCenter for Behavioral Teratology.
TerraMetrics (United States) · US

Funding

Alcohol Research in the Science/Practitioner ModelT32AA013525 · NIAAA · SAN DIEGO STATE UNIVERSITY · PI EDWARD P RILEY, ANDREA SPADONI TOWNSEND · 2002 to 2026
$8.4M
Neural Basis of Emergent Math Difficulties in Healthy Preterm ChildrenR01HD075865 · NICHD · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI AKSHOOMOFF, NATACHA · 2013 to 2017
$3.0M
Mechanisms of Attention Deficits in Children with Heavy Prenatal Alcohol ExposureR01AA019605 · NIAAA · SAN DIEGO STATE UNIVERSITY · PI MATTSON WELLER, SARAH N · 2010 to 2012
$1.1M
Mechanisms of Reading-Related Dysfunction in Fetal Alcohol Spectrum DisordersF31AA022261 · NIAAA · SAN DIEGO STATE UNIVERSITY · PI GLASS, LEILA BETH · 2013 to 2015
$100k
NIAAA NIH HHS F31 AA022261NIAAA NIH HHS R01 AA019605NIAAA NIH HHS T32 AA013525
6 · The paper itself

Abstract

objectiveHeavy prenatal alcohol exposure is associated with impaired school functioning. Spelling performance has not been comprehensively evaluated. We examined whether children with heavy prenatal alcohol exposure demonstrate deficits in spelling and related abilities, including reading, and tested whether there are unique underlying mechanisms for observed deficits in this population.

methodNinety-six school-age children made up 2 groups: children with heavy prenatal alcohol exposure (AE, n = 49) and control children (CON, n = 47). Children completed select subtests from the Wechsler Individual Achievement Test-Second Edition and the NEPSY-II. Group differences and relations between spelling and theoretically related cognitive variables were evaluated using multivariate analysis of variance and Pearson correlations. Hierarchical regression analyses were used to assess contributions of group membership and cognitive variables to spelling performance. The specificity of these deficits and underlying mechanisms was tested by examining the relations between reading ability, group membership, and cognitive variables.

resultsGroups differed significantly on all variables. Group membership and phonological processing significantly contributed to spelling performance, whereas for reading, group membership and all cognitive variables contributed significantly. For both reading and spelling, group × working memory interactions revealed that working memory contributed independently only for alcohol-exposed children.

conclusionAlcohol-exposed children demonstrated a unique pattern of spelling deficits. The relation of working memory to spelling and reading was specific to the AE group, suggesting that if prenatal alcohol exposure is known or suspected, working memory ability should be considered in the development and implementation of explicit instruction.

Indexed as

AchievementReadingAdolescentChildFemaleHumansLanguage Development DisordersMaleMemory, Short-TermPregnancyPrenatal Exposure Delayed EffectsTask Performance and Analysis

Identifiers

PMID25643217
PMCPMC4522410
OpenAlexW2330639876

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.