Evidence map›Paper›PMID 25643159›Full record

ArticlePloS one2015

Proteomics-driven analysis of ovine whey colostrum.

Domenica Scumaci, Francesca Trimboli, Ludovica Dell'Aquila, Antonio Concolino, Giusi Pappaianni, Laura Tammè, Giorgio Vignola, Alessia Luciani, Daniela Morelli, Giovanni Cuda and 2 more

Open access · goldAbstract read
In one paragraph

Article in PloS one, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
3.2field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 24 citations in OpenAlex.

  1. Biologically Active Sheep Colostrum for Topical Treatment and Skin Care.International journal of molecular sciences · 2024
    Article
  2. Article
  3. Article
  4. Article
  5. Review
  6. Article
  7. Article
  8. Use of Proteomics in the Study of Mastitis in Ewes.Pathogens (Basel, Switzerland) · 2019
    Review
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 3 institutions in 1 country.

Domenica ScumaciDpt. of Experimental and Clinical Medicine, Magna Græcia University of Catanzaro, Catanzaro, Italy.
Francesca TrimboliDpt. of Health Science, Magna Græcia University of Catanzaro, Catanzaro, Italy.
Ludovica Dell'AquilaFaculty of Veterinary Medicine, University of Teramo, Teramo, Italy.
Antonio ConcolinoDpt. of Experimental and Clinical Medicine, Magna Græcia University of Catanzaro, Catanzaro, Italy.
Giusi PappaianniDpt. of Experimental and Clinical Medicine, Magna Græcia University of Catanzaro, Catanzaro, Italy.
Laura TammèDpt. of Experimental and Clinical Medicine, Magna Græcia University of Catanzaro, Catanzaro, Italy.
Giorgio VignolaFaculty of Veterinary Medicine, University of Teramo, Teramo, Italy.
Alessia LucianiFaculty of Veterinary Medicine, University of Teramo, Teramo, Italy.
Daniela MorelliIstituto Zooprofilattico Sperimentale dell'Abruzzo e del Molise (IZSAM) "G. Caporale", Teramo, Italy.
Giovanni CudaDpt. of Experimental and Clinical Medicine, Magna Græcia University of Catanzaro, Catanzaro, Italy.
Andrea BoariFaculty of Veterinary Medicine, University of Teramo, Teramo, Italy.
Domenico BrittiDpt. of Health Science, Magna Græcia University of Catanzaro, Catanzaro, Italy.
Magna Graecia University · ITUniversity of Teramo · ITIstituto Zooprofilattico Sperimentale dell'Abruzzo e del Molise G. Caporale · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The aim of this study was to shed light in to the complexity of the ovine colostrum proteome, with a specific focus on the low abundance proteins. The ovine colostrum is characterized by a few dominating proteins, as the immunoglobulins, but it also contains less represented protein species, equally important for the correct development of neonates. Ovine colostrum, collected immediately after lambing, was separated by 1D SDS-PAGE. Proteins bands were digested with trypsin and the resulting peptides were analyzed by LC-MS/MS. On the basis of the Swiss-Prot database, a total of 343 unique proteins were identified. To our knowledge, this study represents the most comprehensive analysis of ovine colostrum proteome.

Indexed as

ProteomicsAnimalsColostrumFemaleGene Expression RegulationGene OntologyLactationMilk ProteinsPregnancySheepWhey ProteinsMilk ProteinsWhey Proteins

Identifiers

PMID25643159
PMCPMC4313942
OpenAlexW2055831680

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.