Evidence map›Paper›PMID 25642841›Full record

ArticleHealth psychology : official journal of the Division of Health Psychology, American Psychological Association2015

From ideas to efficacy: The ORBIT model for developing behavioral treatments for chronic diseases.

Susan M Czajkowski, Lynda H Powell, Nancy Adler, Sylvie Naar-King, Kim D Reynolds, Christine M Hunter, Barbara Laraia, Deborah H Olster, Frank M Perna, Janey C Peterson and 3 more

8 registry-linked trialsOpen access · hybridAbstract read
In one paragraph

Article in Health psychology : official journal of the Division of Health Psychology, American Psychological Association, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 8 registered trials, which are not on this map. Cited by 672 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
672citing papers in PubMed, 2 pooled it
31.4field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04447508 nawithdrawnnot on this mapstarted 2021, after this paper: background citation

Assessing the Feasibility and Acceptability of Reframe Your Pain to Enhance Exercise Adherence in People With Chronic Low Back Pain

TypeinterventionalSponsorUniversity of ManitobaRan2021 to 2023Enrolled0ConditionsLow Back PainArmsParticipants receive one on one motivational interviewing and participate in a group exercise class virtually.
NCT05209373 naunknown statusnot on this mapstarted 2022, after this paper: background citation

Compassionate And Loving Mindset Towards HEART Health riSk (CALM HEARTS 2): A Randomized Optimization Trial

TypeinterventionalSponsorUniversity of ManitobaRan2022 to 2023Enrolled96ConditionsCardiovascular DiseasesArmsIntervention Condition, Positive Control Condition
NCT05926661 nawithdrawnnot on this mapstarted 2023, after this paper: background citation

Support Tool for Families of High-Risk Children With Heart Disease During Hospital Admission and After Discharge

TypeinterventionalSponsorNemours Children's ClinicRan2023 to 2024Enrolled0ConditionsHeart Disease CongenitalArmsNCC Support Toolkit
NCT06592209 nacompletednot on this mapstarted 2023, after this paper: background citation

Body Electric: a Pragmatic Trial Evaluating Movement Breaks As a Public Health Strategy to Mitigate the Harms of Prolonged Sedentary Behavior

TypeinterventionalSponsorColumbia UniversityRan2023 to 2023Enrolled20,217ConditionsSedentary BehaviorArmsSedentary Breaks
NCT06944262 recruitingnot on this mapstarted 2025, after this paper: background citation

Évaluation de la détresse Post-traumatique Relative au Cancer Dans l'année Suivant le Diagnostic Chez Les Patients et Les Aidants et Identification de Leurs Attentes Envers un Accompagnement personnalisé

TypeobservationalSponsorLille UniversityRan2025 to 2028Enrolled350ConditionsCancer, Healthcare Professionnals, Caregiver Distress, Caregiver
NCT07227220 early_phase1completednot on this mapstarted 2025, after this paper: background citation

Leveraging Summer Youth Employment Programs to Prevent Obesity in Adolescents

TypeinterventionalSponsorUniversity of HoustonRan2025 to 2025Enrolled15ConditionsObesity, Childhood, Behavior, Health, Healthy LifestyleArmsSummer Youth Employment Program
NCT07658937 nanot yet recruitingnot on this mapstarted 2026, after this paper: background citation

Improving Sexual and Reproductive Health Communication Between Adolescent and Young Adult Oncology Patients and Clinicians: ReSPECT Intervention Proof-of-Concept Testing

TypeinterventionalSponsorConnecticut Children's Medical CenterRan2026 to 2029Enrolled30ConditionsHealth-Related Quality-of-Life, Cancer, Health CommunicationArmsReSPECT
NCT07722442 nanot yet recruitingnot on this mapstarted 2026, after this paper: background citation

Feasibility, Acceptability and Preliminary Efficacy of a Personalised Behavioural Intervention to Improve Adherence to Dietary and Lifestyle Cancer Prevention Recommendations in Adults Attending Breast and Colorectal Cancer Screening Programmes: A Three-Arm Randomised Pilot Trial (CANVIA)

TypeinterventionalSponsorFundació d'investigació Sanitària de les Illes BalearsRan2026 to 2028Enrolled162ConditionsDietary and Lifestyle Behaviour ChangeArmsPersonalised baseline feedback report, CANVIA mobile app intervention, Additional health professional support
3 · Its place in the literature

Who cites it

672 citing papers in PubMed, 2 syntheses or guidelines pooled it, 1,170 citations in OpenAlex.

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  13. Preliminary evaluation of the acceptability, appropriateness, and feasibility of an online sexual health educational video series for breast cancer patients.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2026
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  18. Mechanisms of change in a randomized control pilot study of partner-involved financial incentive treatments for dual-smoking couples.Health psychology : official journal of the Division of Health Psychology, American Psychological Association · 2025
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612 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 9 institutions in 1 country.

Susan M CzajkowskiClinical Applications and Prevention Branch, Division of Cardiovascular Sciences, National Heart, Lung, and Blood Institute, National Institutes of Health.
Lynda H PowellDepartment of Preventive Medicine, Rush University Medical Center.
Nancy AdlerDepartment of Psychiatry, Center for Health and Community, University of California, San Francisco.
Sylvie Naar-KingPediatric Prevention Research Center, Wayne State University.
Kim D ReynoldsSchool of Community and Global Health, Claremont Graduate University.
Christine M HunterDivision of Diabetes, Endocrinology, and Metabolic Diseases, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health.
Barbara LaraiaDivision of Community Health and Human Development, School of Public Health, University of California, Berkeley.
Deborah H OlsterOffice of Behavioral and Social Sciences Research, Office of the Director, National Institutes of Health.
Frank M PernaBehavioral Research Program, National Cancer Institute, National Institutes of Health.
Janey C PetersonCenter for Integrative Medicine, Weill Cornell Medical College.
Elissa EpelDepartment of Psychiatry, Center for Health and Community, University of California, San Francisco.
Josephine E BoyingtonClinical Applications and Prevention Branch, Division of Cardiovascular Sciences, National Heart, Lung, and Blood Institute, National Institutes of Health.
Mary E CharlsonCenter for Integrative Medicine, Weill Cornell Medical College.
National Institutes of Health · USClaremont Graduate University · USCornell University · USInstitute for Community Health · USNational Heart Lung and Blood Institute · USRush University Medical Center · USUniversity of California, Berkeley · USUniversity of California, San Francisco · USWayne State University · US

Funding

Resource and Coordination UnitU01HL097894 · NHLBI · RUSH UNIVERSITY MEDICAL CENTER · PI POWELL, LYNDA H · 2009 to 2014
$7.1M
SCALE: Small Changes and Lasting EffectsU01HL097843 · NHLBI · WEILL MEDICAL COLL OF CORNELL UNIV · PI CHARLSON, MARY E · 2009 to 2013
$6.5M
Novel interventions to reduce stress induced non-homeostatic eatingU01HL097973 · NHLBI · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI ADLER, NANCY E, EPEL, ELISSA S. · 2009 to 2014
$5.7M
Interventionist Procedures for Adherence to Weight Loss Recs in Black AdolescentsU01HL097889 · NHLBI · WAYNE STATE UNIVERSITY · PI JEN, KAI-LIN CATHERINE, NAAR, SYLVIE · 2009 to 2013
$5.5M
Habitual & Neurocogonitive Processes in Adolescent Obesity PreventionU01HL097839 · NHLBI · CLAREMONT GRADUATE UNIVERSITY · PI REYNOLDS, KIM DANIEL · 2009 to 2014
$5.4M
Increasing Sleep Duration: A Novel Approach to Weight ControlU01CA150387 · NCI · MIRIAM HOSPITAL · PI WING, RENA R · 2009 to 2014
$4.4M
Translating Habituation Research to Interventions for Pediatric ObesityU01DK088380 · NIDDK · STATE UNIVERSITY OF NEW YORK AT BUFFALO · PI EPSTEIN, LEONARD H · 2009 to 2013
$2.9M
INSPIRE: Intervention to Support Participation in Regular Exercise in the ElderlyK23AG042869 · NIA · WEILL MEDICAL COLL OF CORNELL UNIV · PI PETERSON, JANEY CHRISTINE · 2013 to 2016
$671k
NCI NIH HHS U01 CA150387NHLBI NIH HHS U01 HL097839NHLBI NIH HHS U01 HL097843NHLBI NIH HHS U01 HL097889NHLBI NIH HHS U01 HL097894NHLBI NIH HHS U01 HL097973NIA NIH HHS K23 AG042869NIDDK NIH HHS U01 DK088380
6 · The paper itself

Abstract

objectiveGiven the critical role of behavior in preventing and treating chronic diseases, it is important to accelerate the development of behavioral treatments that can improve chronic disease prevention and outcomes. Findings from basic behavioral and social sciences research hold great promise for addressing behaviorally based clinical health problems, yet there is currently no established pathway for translating fundamental behavioral science discoveries into health-related treatments ready for Phase III efficacy testing. This article provides a systematic framework for developing behavioral treatments for preventing and treating chronic diseases.

methodThe Obesity-Related Behavioral Intervention Trials (ORBIT) model for behavioral treatment development features a flexible and progressive process, prespecified clinically significant milestones for forward movement, and return to earlier stages for refinement and optimization.

resultsThis article presents the background and rationale for the ORBIT model, a summary of key questions for each phase, a selection of study designs and methodologies well-suited to answering these questions, and prespecified milestones for forward or backward movement across phases.

conclusionsThe ORBIT model provides a progressive, clinically relevant approach to increasing the number of evidence-based behavioral treatments available to prevent and treat chronic diseases. (PsycINFO Database Record

Indexed as

Behavior TherapyBiomedical ResearchChronic DiseaseHumans

Identifiers

PMID25642841
PMCPMC4522392
OpenAlexW1985326609

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

and 2 more above

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.