Evidence map›Paper›PMID 25642629›Full record

ReviewNanotechnology2015

Challenges in DNA motion control and sequence readout using nanopore devices.

Spencer Carson, Meni Wanunu

Abstract readReview
In one paragraph

Review in Nanotechnology, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 36 papers.

0numbers the graph read from it
0cells of the map it votes in
36citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

36 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Review
  5. Review
  6. Review
  7. Article
  8. Article
  9. Review
  10. Biological Nanopores: Engineering on Demand.Life (Basel, Switzerland) · 2021
    Review
  11. Pore shapes effects on polymer translocation.The European physical journal. E, Soft matter · 2020
    Article
  12. Article
  13. Review
  14. Review
  15. Article
  16. Article
  17. Review
  18. Article
  19. Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Spencer CarsonDepartment of Physics, Northeastern University, Boston, MA 02115, USA.
Meni WanunuDepartment of Physics, Northeastern University, Boston, MA 02115, USA.

Funding

Optimization of Processive Enzymes for DNA Sequencing using NanoporesR01HG006321 · NHGRI · UNIVERSITY OF CALIFORNIA SANTA CRUZ · PI AKESON, MARK A · 2011 to 2013
$3.6M
Picogram-level DNA sequencing using Nanopores and Zero-Mode WaveguidesR21HG006873 · NHGRI · NORTHEASTERN UNIVERSITY · PI KORLACH, JONAS, WANUNU, MENI · 2012 to 2014
$812k
NHGRI NIH HHS R01 HG006321NHGRI NIH HHS R01-HG6321NHGRI NIH HHS R21 HG006873NHGRI NIH HHS R21-HG006873
6 · The paper itself

Abstract

Nanopores are being hailed as a potential next-generation DNA sequencer that could provide cheap, high-throughput DNA analysis. In this review we present a detailed summary of the various sensing techniques being investigated for use in DNA sequencing and mapping applications. A crucial impasse to the success of nanopores as a reliable DNA analysis tool is the fast and stochastic nature of DNA translocation. We discuss the incorporation of biological motors to step DNA through a pore base-by-base, as well as the many experimental modifications attempted for the purpose of slowing and controlling DNA transport.

Indexed as

NanoporesBiosensing TechniquesDNADNA DamageElectrochemistryElectronicsEnzymesGraphiteHemolysin ProteinsHumansIonsMotionNanotechnologyNanotubes, CarbonSequence Analysis, DNAStochastic ProcessesDNAEnzymesGraphiteHemolysin ProteinsIonsNanotubes, Carbon

Identifiers

PMID25642629
PMCPMC4710574

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.