ArticleJournal of ophthalmology2015
Association between Glucose Levels and Intraocular Pressure: Pre- and Postprandial Analysis in Diabetic and Nondiabetic Patients.
Article in Journal of ophthalmology, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.
What it found
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Who cites it
16 citing papers in PubMed, 41 citations in OpenAlex.
- The Sigma-1 Receptor Agonist Fluvoxamine Is Protective in Hyperglycaemia-Induced Dysfunction of Trabecular Meshwork Cells.Pharmaceuticals (Basel, Switzerland) · 2026Article
- Intraocular pressure variation (ocular hypertension) in diabetes mellitus.World journal of clinical cases · 2025Review
- Article
- Association of stage of diabetic retinopathy on intraocular pressure.Digital journal of ophthalmology : DJO · 2025Article
- Relationship between hyperglycemia and intraocular pressure, corneal biomechanics, and corneal topography during the oral glucose tolerance test in nondiabetic patients.International ophthalmology · 2024Article
- Factors Associated with Increased Intraocular Pressure in Type 2 Diabetes Patients.Journal of clinical medicine · 2024Article
- Change of Intraocular Pressure Over 5 Years and its Relationship to Cardiovascular Parameters: Results From the Gutenberg Health Study.Investigative ophthalmology & visual science · 2024Article
- Risk factors associated with elevated intraocular pressure: a population-based study in a rural community of Bangladesh.BMJ open ophthalmology · 2023Article
- Distribution and associated factors of intraocular pressure in the older population: Tehran Geriatric Eye Study.International journal of ophthalmology · 2023Article
- Diabetes mellitus and incident glaucoma in Australia: a 10-year cohort study from the 45 and Up Study.Annals of translational medicine · 2022Article
- Serum Calcium Level as a Useful Surrogate for Risk of Elevated Intraocular Pressure.Journal of clinical medicine · 2021Article
- Relationships of diabetes and hyperglycaemia with intraocular pressure in a Japanese population: the JPHC-NEXT Eye Study.Scientific reports · 2020Article
- Genetic Correlations Between Diabetes and Glaucoma: An Analysis of Continuous and Dichotomous Phenotypes.American journal of ophthalmology · 2019Article
- Metabolic syndrome as a risk factor for high intraocular pressure: the Korea National Health and Nutrition Examination Survey 2008-2010.Diabetes, metabolic syndrome and obesity : targets and therapy · 2019Article
- Article
- Peak, Fluctuation, or Mean? A Correlation Analysis of Long-term Intraocular Pressure Variation Parameters in Patients with Stable Glaucoma.Journal of current glaucoma practiceArticle
Corrections and comments
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Authors and funding
5 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The aim of this study was to evaluate the relationship between glucose levels and intraocular pressure (IOP) fluctuation in diabetic and nondiabetic patients. Seventeen nondiabetic and 20 diabetic subjects underwent a complete ophthalmic examination, capillary glucose testing, and applanation tonometry in two distinct situations: first, fasting for at least 8 hours and, second, postprandial measurements. Baseline glucose levels were higher in diabetic patients (P < 0.001). Postprandial IOP was significantly higher than baseline IOP in diabetic (P < 0.001) and nondiabetic patients (P = 0.006). Postprandial glucose levels were significantly higher than baseline measurements in both diabetic (P = 0.005) and nondiabetic patients (P = 0.015). There was a significant association between glucose levels variation and IOP change in both diabetic patients (R (2) = 0.540; P < 0.001) and nondiabetic individuals (R (2) = 0.291; P = 0.025). There is also a significant association between the baseline glucose levels and IOP change in diabetic group (R (2) = 0.445; P = 0.001). In a multivariable model, the magnitude of glucose level change remained significantly associated with IOP variation even including age, baseline IOP, ancestry, and gender as a confounding factor (P < 0.001). We concluded that there is a significant association between blood glucose levels and IOP variation, especially in diabetic patients.
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Registered trials
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