ArticleRSC advances2015
Alginate-peptide amphiphile core-shell microparticles as a targeted drug delivery system.
Article in RSC advances, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
21 citing papers in PubMed.
- Bridging stimulus-responsive and dissipative peptide assemblies to build complex interactive biomaterials.Nature reviews. Chemistry · 2026Review
- Supramolecular Nanozymes Based on Self-Assembly of Biomolecule for Cancer Therapy.International journal of nanomedicine · 2025Review
- Padina Minor Extract Confers Resistance against Candida Albicans Infection: Evaluation in a Zebrafish Model.Biology · 2024Article
- Peptide Amphiphiles as Biodegradable Adjuvants for Efficient Retroviral Gene Delivery.Advanced healthcare materials · 2024Article
- Peptide-Based Supramolecular Hydrogels as Drug Delivery Agents: Recent Advances.Gels (Basel, Switzerland) · 2022Review
- Investigating the effects of N-terminal acetylation on KFE8 self-assembly with 2D IR spectroscopy.Biophysical journal · 2022Article
- Supramolecular peptide nano-assemblies for cancer diagnosis and therapy: from molecular design to material synthesis and function-specific applications.Journal of nanobiotechnology · 2021Review
- Self-assembled peptide and protein nanostructures for anti-cancer therapy: Targeted delivery, stimuli-responsive devices and immunotherapy.Nano today · 2021Article
- Versatile Types of Polysaccharide-Based Drug Delivery Systems: From Strategic Design to Cancer Therapy.International journal of molecular sciences · 2020Review
- Covalent co-assembly between resilin-like polypeptide and peptide amphiphile into hydrogels with controlled nanostructure and improved mechanical properties.Biomaterials science · 2020Article
- Multicomponent peptide assemblies.Chemical Society reviews · 2018Review
- Intracellular delivery and ultrasonic activation of folate receptor-targeted phase-change contrast agents in breast cancer cells in vitro.Journal of controlled release : official journal of the Controlled Release Society · 2016Article
- Bio-inspired supramolecular materials by orthogonal self-assembly of hydrogelators and phospholipids.Chemical science · 2016Article
- Targeted photo-chemo therapy of malignancy on the chest wall while cardiopulmonary avoidance based on Fe3O4@ZnO nanocomposites.Oncotarget · 2016Article
- Supramolecular Nanofibers Enhance Growth Factor Signaling by Increasing Lipid Raft Mobility.Nano letters · 2016Article
- Energy landscapes and functions of supramolecular systems.Nature materials · 2016Article
- Self-assembled peptide-based nanostructures: Smart nanomaterials toward targeted drug delivery.Nano today · 2016Article
- Biopolymers and supramolecular polymers as biomaterials for biomedical applications.MRS bulletin · 2015Article
- Co-assembly, spatiotemporal control and morphogenesis of a hybrid protein-peptide system.Nature chemistry · 2015Article
- Synthesis and Adsorption Property of SiO₂@Co(OH)₂ Core-Shell Nanoparticles.Nanomaterials (Basel, Switzerland) · 2015Article
Corrections and comments
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Authors and funding
7 authors.
Funding
Abstract
We describe in this work the synthesis of microparticles with a doxorubicin drug conjugated alginate core and a shell of peptide amphiphile nanofibres functionalized for targeting the folate receptor. The spherical geometry of the particle core allows high drug loading per surface area, whereas the nanoscale fibrous shell formed by self-assembly of peptide amphiphiles offers a high surface to volume ratio that is ideal for targeting. The synthesised microparticles have a 60-fold higher cytotoxicity against MDA-MB-231 breast cancer cells compared to non-targeting particles.
Identifiers
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.