ArticleEmerging themes in epidemiology2014
Risk factors for tuberculosis in older children and adolescents: a matched case-control study in Recife, Brazil.
Article in Emerging themes in epidemiology, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 1 of them a synthesis that pooled it.
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Who cites it
12 citing papers in PubMed, 1 synthesis or guideline pooled it, 31 citations in OpenAlex.
- Risk factors for the development of tuberculosis among the pediatric population: a systematic review and meta-analysis.European journal of pediatrics · 2023Pooled it
- Understanding the relationship between adolescents with tuberculosis and health services: an indepth qualitative study from Cape Town.BMJ open · 2025Observational
- Performance of a score to characterise adequate contact among the social network of persons with TB.IJTLD open · 2024Article
- The geographical distribution and socioeconomic risk factors of COVID-19, tuberculosis and leprosy in Fortaleza, Brazil.BMC infectious diseases · 2023Article
- Pulmonary tuberculosis and multidrug-resistantFrontiers in medicine · 2023Article
- Drug-Resistant Tuberculosis Treatment Outcomes among Children and Adolescents in Karachi, Pakistan.Tropical medicine and infectious disease · 2022Article
- Tuberculosis in Adolescents and Young Adults: Emerging Data on TB Transmission and Prevention among Vulnerable Young People.Tropical medicine and infectious disease · 2021Review
- The Effectiveness of Tuberculosis Education Programme in Kelantan, Malaysia on Knowledge, Attitude, Practice and Stigma Towards Tuberculosis among Adolescents.The Malaysian journal of medical sciences : MJMS · 2020Article
- Prevalence, Associated Risk Factors and Rifampicin Resistance Pattern of Pulmonary Tuberculosis Among Children at Debre Markos Referral Hospital, Northwest, Ethiopia.Infection and drug resistance · 2020Article
- Pediatric Tuberculosis in a Northeast State of Peninsular Malaysia: Diagnostic Classifications and Determinants.Oman medical journal · 2019Article
- Tuberculosis Transmission in Households and Classrooms of Adolescent Cases Compared to the Community in China.International journal of environmental research and public health · 2018Article
- Abdominal tuberculosis manifested as tuberculosis of the urachal sinus in an adolescent and the role of laparoscopy in the management: a rare case report.BMC infectious diseases · 2016Article
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Authors and funding
4 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundTuberculosis is a major disease worldwide and most research focus on risk factors for adults, although there is a marked adolescent peak in incidence. The objective of this study was to identify risk factors for tuberculosis in children aged 7 to 19.
methodsA case control study matched by age with 169 cases and 477 controls. The study population consisted of adolescents and older children from Recife, Brazil. Cases were individuals diagnosed with tuberculosis in the control programme and controls were selected in the neighborhood of cases. Conditional logistic regression was used to identify risk factors.
resultsCigarette smoking increased by 50% the risk of tuberculosis but that this was not statistically significant (OR = 1.6). Other risk factors were sleeping in the same house as a case of tuberculosis (OR = 31.6), living in a house with no piped water (OR = 7.7) (probably as a proxy for bad living conditions), illiteracy (OR = 3.7) and male sex (OR = 1.8). The increase in risk with living in houses with no piped water was much more marked in males. The proportion of cases of tuberculosis attributed to contact with someone with TB was 38% and to illiteracy, lack of piped water and smoking, 20%.
conclusionHousehold contact with tuberculosis, social factors and male sex play the biggest role in determining risk of TB disease among children and adolescents in the study. We recommend further research on the relationship of cigarette smoking on tuberculosis in adolescents, and on whether the sex differentials are more marked in bad living conditions. Separate studies should be conducted in older children and in adolescents.
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