ReviewFrontiers in microbiology2014
Skeletal cryptococcosis from 1977 to 2013.
Review in Frontiers in microbiology, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
26 citing papers in PubMed, 1 synthesis or guideline pooled it, 42 citations in OpenAlex.
- Global guideline for the diagnosis and management of cryptococcosis: an initiative of the ECMM and ISHAM in cooperation with the ASM.The Lancet. Infectious diseases · 2024Guideline
- Rare case of ulnar cryptococcal osteomyelitis in a 26-year-old immunocompetent patient.Radiology case reports · 2026Article
- Diagnosis of a patient with pulmonary and skeletal cryptococcosis: A case report and literature review.The Journal of international medical research · 2026Review
- Cryptococcal Osteomyelitis in a Virally Suppressed Adolescent Living With HIV: A Case Report.Case reports in infectious diseases · 2026Article
- Cryptococcus neoformans tibial osteomyelitis in an immunocompetent host: a case diagnosed by tNGS.BMC infectious diseases · 2025Article
- Disseminated Skeletal Cryptococcosis: A Case Report.Journal of orthopaedic case reports · 2025Article
- Disseminated Cryptococcus infection presenting as lytic skeletal lesions suggesting bony metastatic disease.Skeletal radiology · 2024Article
- Design of an epitope-based peptide vaccine against Cryptococcus neoformans.FEBS open bio · 2024Article
- Disseminated Cryptococcus neoformans infection involving multiple bones and lung in an immunocompetent patient: a case report.BMC infectious diseases · 2024Article
- Cryptococcus Neoformans Osteomyelitis of the Right Ankle Diagnosed by Metagenomic Next-Generation Sequencing in a HIV-Negative Patient with Tuberculous Lymphadenitis and Pulmonary Tuberculosis: A Case Report and Recent Literature Review.Infection and drug resistance · 2024Article
- An unusual recurrent case ofMedical mycology case reports · 2023Article
- Cryptococcal Osteomyelitis of the Left Acetabulum: A Case Report.Current medical imaging · 2023Article
- Osteoarticular Mycoses.Clinical microbiology reviews · 2022Review
- Primary Cutaneous Cryptococcosis Caused byTropical medicine and infectious disease · 2022Article
- Review
- Isolated cryptococcal osteomyelitis of the ulna in an immunocompetent patient: A case report.World journal of clinical cases · 2022Article
- Pubis Cryptococcal Osteomyelitis in an Immunocompetent Patient: A Case Report and Recent Literature Review.Infection and drug resistance · 2022Article
- Treatment recommendations for non-HIV associated cryptococcal meningoencephalitis including management of post-infectious inflammatory response syndrome.Frontiers in neurology · 2022Review
- Disseminated Cryptococcal Infection of the Lumbar Spine in an Immunocompetent Man.Infection and drug resistance · 2022Article
- Associations betweenJournal of fungi (Basel, Switzerland) · 2021Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Skeletal cryptococcosis, an aspect of disseminated cryptococcal disease or isolated skeletal cryptococcal infection, is a rare but treatable disease. However, limited information is available regarding its clinical features, treatment, and prognosis. This systematic review examined all cases published between April 1977 and May 2013 with regard to the factors associated with this disease, including patient sex, age, and epidemiological history; affected sites; clinical symptoms; underlying diseases; laboratory tests; radiological manifestations; and delays in diagnosis, treatment, follow-up assessments, and outcomes. We found that immune abnormality is a risk factor but does not predict mortality; these observations are due to recent Cryptococcus neoformans var gattii (CNVG) outbreaks (Chaturvedi and Chaturvedi, 2011). Dissemination was irrespective of immune status and required combination therapy, and dissemination carried a worse prognosis. Therefore, a database of skeletal cryptococcosis cases should be created.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.