Evidence map›Paper›PMID 25641994›Full record

ArticleTetrahedron letters2015

Hydrogen-deuterium exchange of aromatic amines and amides using deuterated trifluoroacetic acid.

Richard Giles, Amy Lee, Erica Jung, Aaron Kang, Kyung Woon Jung

Open access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Tetrahedron letters, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.6field-weighted citation impact, top 35% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 21 citations in OpenAlex.

  1. Rhodium-catalyzedChemical science · 2026
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Richard GilesLoker Hydrocarbon Research Institute and Department of Chemistry, University of Southern California, Los Angeles, California 90089, USA.
Amy LeeLoker Hydrocarbon Research Institute and Department of Chemistry, University of Southern California, Los Angeles, California 90089, USA.
Erica JungLoker Hydrocarbon Research Institute and Department of Chemistry, University of Southern California, Los Angeles, California 90089, USA.
Aaron KangLoker Hydrocarbon Research Institute and Department of Chemistry, University of Southern California, Los Angeles, California 90089, USA.
Kyung Woon JungLoker Hydrocarbon Research Institute and Department of Chemistry, University of Southern California, Los Angeles, California 90089, USA.
University of Southern California · US

Funding

Acquisition of a 500 MHz NMR Spectrometer for the University of Southern CalifS10RR025432 · NCRR · UNIVERSITY OF SOUTHERN CALIFORNIA · PI JUNG, KYUNG W. · 2009 to 2009
$500k
NCRR NIH HHS S10 RR025432
6 · The paper itself

Abstract

The H-D exchange of aromatic amines and amides, including pharmaceutically relevant compounds such as acetaminophen and diclofenac, was investigated using CF

Indexed as

AcetaminophenBrønsted acidCF3COODElectrophilic aromatic substitutionH-D exchange

Identifiers

PMID25641994
PMCPMC4310004
OpenAlexW2012245634

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.