Evidence map›Paper›PMID 25641538›Full record

ArticleAmerican heart journal2015

Factors associated with variations in hospital expenditures for acute heart failure in the United States.

Boback Ziaeian, Puza P Sharma, Tzy-Chyi Yu, Katherine Waltman Johnson, Gregg C Fonarow

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in American heart journal, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed, 4 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 4 syntheses or guidelines pooled it.

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  18. Epidemiology and aetiology of heart failure.Nature reviews. Cardiology · 2016
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Boback ZiaeianDivision of Cardiology, David Geffen School of Medicine at UCLA, Los Angeles, CA; Jonathan and Karin Fielding School of Public Health at UCLA, Los Angeles, CA.
Puza P SharmaNovartis Pharmaceuticals Corporation, East Hanover, NJ.
Tzy-Chyi YuNovartis Pharmaceuticals Corporation, East Hanover, NJ.
Katherine Waltman JohnsonNovartis Pharmaceuticals Corporation, East Hanover, NJ.
Gregg C FonarowAhmanson-UCLA Cardiomyopathy Center, UCLA Medical Center, Los Angeles, CA. Electronic address: gfonarow@mednet.ucla.edu.

Funding

CARDIOVASCULAR SCIENTIST TRAINING PROGRAMT32HL007895 · NHLBI · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI SHIVKUMAR, KALYANAM, WATSON, KAROL E · 1998 to 2023
$9.2M
NHLBI NIH HHS T32 HL007895
6 · The paper itself

Abstract

backgroundRelatively little contemporary data are available that describe differences in acute heart failure (AHF) hospitalization expenditures as a function of patient and hospital characteristics, especially from a population-based investigation. This study aimed to evaluate factors associated with variations in hospital expenditures for AHF in the United States.

methodsA cross-sectional analysis using discharge data from the 2011 Nationwide Inpatient Sample, Healthcare Cost and Utilization Project, was conducted. Discharges with primary International Classification of Diseases, Ninth Revision, Clinical Modification, diagnosis codes for AHF in adults were included. Costs were estimated by converting Nationwide Inpatient Sample charge data using the Healthcare Cost and Utilization Project Cost-to-Charge Ratio File. Discharges with highest (≥80th percentile) versus lowest (≤20th percentile) costs were compared for patient characteristics, hospital characteristics, utilization of procedures, and outcomes.

resultsOf the estimated 1 million AHF hospital discharges, the mean cost estimates were $10,775 per episode. Younger age, higher percentage of obesity, atrial fibrillation, pulmonary disease, fluid/electrolyte disturbances, renal insufficiency, and greater number of cardiac/noncardiac procedures were observed in stays with highest versus lowest costs. Highest-cost discharges were more likely to be observed in urban and teaching hospitals. Highest-cost AHF discharges also had 5 times longer length of stay, were 9 times more costly, and had higher in-hospital mortality (5.6% vs 3.5%) compared with discharges with lowest costs (all P < .001).

conclusionsAcute heart failure hospitalizations are costly. Expenditures vary markedly among AHF hospitalizations in the United States, with substantial differences in patient and hospital characteristics, procedures, and in-hospital outcomes among discharges with highest compared with lowest costs.

Indexed as

Heart FailureAdultAgedAged, 80 and overAge FactorsAnalysis of VarianceComorbidityCross-Sectional StudiesFemaleHealth ExpendituresHospital CostsHospitalizationHospital MortalityHospitals, UrbanHumansLength of Stay

Identifiers

PMID25641538
PMCPMC4316377

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.