ArticleThe Journal of pediatrics2015
Racial/ethnic differences in survival of United States children with birth defects: a population-based study.
Article in The Journal of pediatrics, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 47 papers, 4 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
47 citing papers in PubMed, 4 syntheses or guidelines pooled it, 85 citations in OpenAlex.
- The Association of Race and Ethnicity with Mortality in Pediatric Patients with Congenital Heart Disease: a Systematic Review.Journal of racial and ethnic health disparities · 2024Pooled it
- Neonatal and infant mortality associated with spina bifida: A systematic review and meta-analysis.PloS one · 2021Pooled it
- Long-term survival of children born with congenital anomalies: A systematic review and meta-analysis of population-based studies.PLoS medicine · 2020Pooled it
- Long-Term Survival of Individuals Born With Congenital Heart Disease: A Systematic Review and Meta-Analysis.Journal of the American Heart Association · 2016Pooled it
- Epidemiologic Features of Preterm Birth Among Infants With Trisomy 21 in Texas, 1999-2018.American journal of medical genetics. Part A · 2026Article
- Long-term outcomes of children born with neural-tube defects in Botswana.BMC pediatrics · 2025Article
- Neighborhood Income Disparities in Unplanned Hospital Admission and In-Hospital Outcomes Among Children with Congenital Heart Disease.Pediatric cardiology · 2025Article
- Mortality in Cleft Lip and Palate Patients: A Systematic Review and Meta-analysis.Plastic and reconstructive surgery. Global open · 2025Article
- Racial disparities in maternal exposure to ambient air pollution during pregnancy and prevalence of congenital heart defects.American journal of epidemiology · 2025Article
- Association of birth defects during the perinatal period with child mortality under 5 years.Frontiers in pediatrics · 2025Article
- Survival of Children With Critical Congenital Heart Defects in the National Birth Defects Prevention Study.Birth defects research · 2024Article
- Scientific impact of the National Birth Defects Prevention Network multistate collaborative publications.Birth defects research · 2024Review
- Survival of neonates, infants, and children with birth defects: a population-based study in Texas, 1999-2018.Lancet regional health. Americas · 2023Article
- Healthcare experiences of patients with Down syndrome from primarily Spanish-speaking households.American journal of medical genetics. Part A · 2023Article
- Causes of death in children with congenital anomalies up to age 10 in eight European countries.BMJ paediatrics open · 2023Article
- Healthcare experiences of patients with Down syndrome who are Black, African American, of African descent, or of mixed race.American journal of medical genetics. Part A · 2023Article
- Maternal cigarette smoking and alcohol consumption and congenital diaphragmatic hernia.Birth defects research · 2022Article
- Spina Bifida: A Review of the Genetics, Pathophysiology and Emerging Cellular Therapies.Journal of developmental biology · 2022Review
- Addressing Social Determinants of Health and Mitigating Health Disparities Across the Lifespan in Congenital Heart Disease: A Scientific Statement From the American Heart Association.Journal of the American Heart Association · 2022Review
- Multijurisdictional Analyses of Birth Defects: Considering the Common Data Model Approach.Pediatrics · 2022Article
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Authors and funding
12 authors at 9 institutions in 1 country.
Funding
Abstract
objectivesTo examine racial/ethnic-specific survival of children with major birth defects in the US. STUDY
designWe pooled data on live births delivered during 1999-2007 with any of 21 birth defects from 12 population-based birth defects surveillance programs. We used the Kaplan-Meier method to calculate cumulative survival probabilities and Cox proportional hazards models to estimate mortality risk.
resultsFor most birth defects, there were small-to-moderate differences in neonatal (<28 days) survival among racial/ethnic groups. However, compared with children born to non-Hispanic white mothers, postneonatal infant (28 days to <1 year) mortality risk was significantly greater among children born to non-Hispanic black mothers for 13 of 21 defects (hazard ratios [HRs] 1.3-2.8) and among children born to Hispanic mothers for 10 of 21 defects (HRs 1.3-1.7). Compared with children born to non-Hispanic white mothers, a significantly increased childhood (≤ 8 years) mortality risk was found among children born to Asian/Pacific Islander mothers for encephalocele (HR 2.6), tetralogy of Fallot, and atrioventricular septal defect (HRs 1.6-1.8) and among children born to American Indian/Alaska Native mothers for encephalocele (HR 2.8), whereas a significantly decreased childhood mortality risk was found among children born to Asian/Pacific Islander mothers for cleft lip with or without cleft palate (HR 0.6).
conclusionChildren with birth defects born to non-Hispanic black and Hispanic mothers carry a greater risk of mortality well into childhood, especially children with congenital heart defect. Understanding survival differences among racial/ethnic groups provides important information for policy development and service planning.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.