ArticleNeuropsychologia2015
Perceptual, cognitive, and personality rigidity in Parkinson's disease.
Article in Neuropsychologia, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07748715 (Blue Color Processing in the Eye as a Biomarker of Brain Dopamine), which is not on this map. Cited by 9 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Blue Color Processing in the Eye as a Biomarker of Brain Dopamine
Who cites it
9 citing papers in PubMed, 25 citations in OpenAlex.
- Perceiving the uncertain: predictive coding and individual differences in the dynamics of multistable perception.Cognitive processing · 2026Review
- Outlining a novel psychometric model of mental flexibility and affect dynamics.Frontiers in psychology · 2023Review
- Mental flexibility assessment: A research protocol for patients with Parkinson's Disease and Anorexia Nervosa.PloS one · 2023Article
- Increasing Contrast Improves Object Perception in Parkinson's Disease with Visual Hallucinations.Movement disorders clinical practice · 2021Article
- Neuroticism, Smoking, and the Risk of Parkinson's Disease.Journal of Parkinson's disease · 2021Article
- Bistable perception in normal aging: perceptual reversibility and its relation to cognition.Neuropsychology, development, and cognition. Section B, Aging, neuropsychology and cognition · 2017Article
- Optokinetic nystagmus reflects perceptual directions in the onset binocular rivalry in Parkinson's disease.PloS one · 2017Article
- Which figure copy test is more sensitive for cognitive impairment in Parkinson's disease: Wire cube or interlocking pentagons?Clinical neurology and neurosurgery · 2015Article
- Effect of visual cues on the resolution of perceptual ambiguity in Parkinson's disease and normal aging.Journal of the International Neuropsychological Society : JINS · 2015Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors at 2 institutions in 1 country.
Funding
Abstract
Parkinson's disease (PD) is associated with motor and non-motor rigidity symptoms (e.g., cognitive and personality). The question is raised as to whether rigidity in PD also extends to perception, and if so, whether perceptual, cognitive, and personality rigidities are correlated. Bistable stimuli were presented to 28 non-demented individuals with PD and 26 normal control adults (NC). Necker cube perception and binocular rivalry were examined during passive viewing, and the Necker cube was additionally used for two volitional-control conditions: Hold one percept in front, and Switch between the two percepts. Relative to passive viewing, PD were significantly less able than NC to reduce dominance durations in the Switch condition, indicating perceptual rigidity. Tests of cognitive flexibility and a personality questionnaire were administered to explore the association with perceptual rigidity. Cognitive flexibility was not correlated with perceptual rigidity for either group. Personality (novelty seeking) correlated with dominance durations on Necker passive viewing for PD but not NC. The results indicate the presence in mild-moderate PD of perceptual rigidity and suggest shared neural substrates with novelty seeking, but functional divergence from those supporting cognitive flexibility. The possibility is raised that perceptual rigidity may be a harbinger of cognitive inflexibility later in the disease course.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.