Letter to the editor regarding "GJB2, GJB6 or GJA1 genes should not be investigated in routine in non syndromic deafness in people of sub-Saharan African descent".

Ambroise Wonkam

Abstract readLetterComment

In one paragraph

Article in International journal of pediatric otorhinolaryngology, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it

0cells of the map it votes in

12citing papers in PubMed

1.2field-weighted citation impact, top 26% of its field

1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 15 citations in OpenAlex.

Etiologies of Early-Onset Hearing Impairment in Rwanda.Genes · 2025
Article
A novel autosomal dominant GREB1L variant associated with non-syndromic hearing impairment in Ghana.BMC medical genomics · 2022
Article
Exome sequencing of families from Ghana reveals known and candidate hearing impairment genes.Communications biology · 2022
Article
Hearing loss in Africa: current genetic profile.Human genetics · 2022
Review
A novel variant inExperimental biology and medicine (Maywood, N.J.) · 2021
Article
Enhancing Genetic Medicine: Rapid and Cost-Effective Molecular Diagnosis for aGenes · 2020
Article
Returning incidental findings in African genomics research.Nature genetics · 2020
Article
Perceptions of parents of children with hearing loss of genetic origin in South Africa.Journal of community genetics · 2019
Article
Frontiers in genetics · 2019
Article
Public Health Burden of Hearing Impairment and the Promise of Genomics and Environmental Research: A Case Study in Ghana, Africa.Omics : a journal of integrative biology · 2017
Review
Genomic Medicine Without Borders: Which Strategies Should Developing Countries Employ to Invest in Precision Medicine? A New "Fast-Second Winner" Strategy.Omics : a journal of integrative biology · 2017
Article
Success stories in genomic medicine from resource-limited countries.Human genomics · 2015
Article

4 · The record

Corrections and comments

Comment on
Common genes for non-syndromic deafness are uncommon in sub-Saharan Africa: a report from Nigeria.2014

5 · Who and what money

Authors and funding

1 author at 1 institution in 1 country.

Ambroise WonkamDivision of Human Genetics, Faculty of Health Sciences, University of Cape Town (UCT), South Africa. Electronic address: ambroise.wonkam@uct.ac.za.

University of Cape Town · ZA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Black PeopleConnexin 26ConnexinsDeafnessFemaleHumansMaleConnexin 26ConnexinsGJB2 protein, humanCameroonGJB2GJB6 and GJA1Non-syndromic deafnessSub-Saharan Africa

Identifiers

PMID25639550

DOI10.1016/j.ijporl.2015.01.012

OpenAlexW2061287515

What OpenQuestion holds

Textmetadata

Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.