ArticleBehavioural processes2015
Quantitative analysis of performance on a progressive-ratio schedule: effects of reinforcer type, food deprivation and acute treatment with Δ⁹-tetrahydrocannabinol (THC).
Article in Behavioural processes, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.
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Who cites it
15 citing papers in PubMed.
- Article
- Efficacy of Edible and Leisure Reinforcers with Domestic Dogs.Animals : an open access journal from MDPI · 2023Article
- Training-induced circuit-specific excitatory synaptogenesis in mice is required for effort control.Nature communications · 2023Article
- Chronic restraint stress impairs voluntary wheel running but has no effect on food-motivated behavior in mice.Brain, behavior, and immunity · 2023Article
- Appetitive, antinociceptive, and hypothermic effects of vaped and injected Δ-9-tetrahydrocannabinol (THC) in rats: exposure and dose-effect comparisons by strain and sex.Pharmacology, biochemistry, and behavior · 2021Article
- Article
- Motivation to run measured by progressive ratio tests: Failure to support the addiction hypothesis for rats.Learning & behavior · 2019Article
- Ovarian Hormones Mediate Changes in Adaptive Choice and Motivation in Female Rats.Frontiers in behavioral neuroscience · 2019Article
- A Touchscreen Motivation Assessment Evaluated in Huntington's Disease Patients and R6/1 Model Mice.Frontiers in neurology · 2019Article
- Validation and optimisation of a touchscreen progressive ratio test of motivation in male rats.Psychopharmacology · 2018Article
- Evaluation of reinforcing and aversive effects of voluntary ΔNeuropharmacology · 2018Article
- Suppressive and enhancing effects of nicotine on food-seeking behavior.Behavioural brain research · 2018Article
- Optimisation of cognitive performance in rodent operant (touchscreen) testing: Evaluation and effects of reinforcer strength.Learning & behavior · 2017Article
- Optimizing reproducibility of operant testing through reinforcer standardization: identification of key nutritional constituents determining reward strength in touchscreens.Molecular brain · 2017Article
- Activation of Ventral Tegmental Area 5-HTNeuropsychopharmacology : official publication of the American College of Neuropsychopharmacology · 2017Article
Corrections and comments
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5 authors.
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Abstract
Rats' performance on a progressive-ratio schedule maintained by sucrose (0.6M, 50 μl) and corn oil (100%, 25 μl) reinforcers was assessed using a model derived from Killeen's (1994) theory of schedule-controlled behaviour, 'Mathematical Principles of Reinforcement'. When the rats were maintained at 80% of their free-feeding body weights, the parameter expressing incentive value, a, was greater for the corn oil than for the sucrose reinforcer; the response-time parameter, δ, did not differ between the reinforcer types, but a parameter derived from the linear waiting principle (T0), indicated that the minimum post-reinforcement pause was longer for corn oil than for sucrose. When the rats were maintained under free-feeding conditions, a was reduced, indicating a reduction of incentive value, but δ was unaltered. Under the food-deprived condition, the CB1 cannabinoid receptor agonist Δ(9)-tetrahydrocannabinol (THC: 0.3, 1 and 3 mg kg(-1)) increased the value of a for sucrose but not for corn oil, suggesting a selective enhancement of the incentive value of sucrose; none of the other parameters was affected by THC. The results provide new information about the sensitivity of the model's parameters to deprivation and reinforcer quality, and suggest that THC selectively enhances the incentive value of sucrose.
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