Evidence map›Paper›PMID 25637639›Full record

ReviewNephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association2016

Caring for patients with kidney disease: shifting the paradigm from evidence-based medicine to patient-centered care.

Ann M O'Hare, Rudolph A Rodriguez, Christopher Barrett Bowling

Abstract readReview
In one paragraph

Review in Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Trial
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  4. Article
  5. Establishing Research Priorities in Geriatric Nephrology: A Delphi Study of Clinicians and Researchers.American journal of kidney diseases : the official journal of the National Kidney Foundation · 2025
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  7. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Ann M O'HareHospital and Specialty Medicine Service, VA Puget Sound Health Care System, Seattle, WA, USA Health Services Research and Development Center of Innovation, VA Puget Sound Health Care System, Seattle, WA, USA Department of Medicine, University of Washington, Seattle, WA, USA.
Rudolph A RodriguezHospital and Specialty Medicine Service, VA Puget Sound Health Care System, Seattle, WA, USA Department of Medicine, University of Washington, Seattle, WA, USA.
Christopher Barrett BowlingBirmingham/Atlanta Geriatric Research, Education, and Clinical Center, Atlanta VA Medical Center, Decatur, GA, USA Department of Medicine, Emory University, Atlanta, GA, USA.

Funding

USRDS Special Study Center on Palliative and End-of-Life CareU01DK102150 · NIDDK · UNIVERSITY OF WASHINGTON · PI KURELLA TAMURA, MANJULA, O'HARE, ANN M. · 2014 to 2018
$2.6M
Reasons for the Excess Mortality and Functional Decline in Older Adults with CKDR03AG042336 · NIA · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI BOWLING, CHRISTOPHER BARRETT · 2012 to 2013
$142k
Advance care planning in Veterans with kidney diseaseI01HX000961 · VA · VA PUGET SOUND HEALTHCARE SYSTEM · PI O'HARE, ANN M. · 2014 to 2014
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Trajectories of Kidney Dysfunction in Older Adults with Chronic Kidney DiseaseIK2CX000856 · VA · VETERANS HEALTH ADMINISTRATION · PI BOWLING, CHRISTOPHER BARRETT · 2013 to 2017
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CSRD VA IK2 CX000856HSRD VA I01 HX000961NIA NIH HHS R03 AG042336NIA NIH HHS R03AG042336-01NIDDK NIH HHS U01 DK102150NIDDK NIH HHS U01DK102150-01PHS HHS IAA 14FED1405094-0001
6 · The paper itself

Abstract

The last several decades have witnessed the emergence of evidence-based medicine as the dominant paradigm for medical teaching, research and practice. Under an evidence-based approach, populations rather than individuals become the primary focus of investigation. Treatment priorities are largely shaped by the availability, relevance and quality of evidence and study outcomes and results are assumed to have more or less universal significance based on their implications at the population level. However, population-level treatment goals do not always align with what matters the most to individual patients-who may weigh the risks, benefits and harms of recommended treatments quite differently. In this article we describe the rise of evidence-based medicine in historical context. We discuss limitations of this approach for supporting real-world treatment decisions-especially in older adults with confluent comorbidity, functional impairment and/or limited life expectancy-and we describe the emergence of more patient-centered paradigms to address these limitations. We explain how the principles of evidence-based medicine have helped to shape contemporary approaches to defining, classifying and managing patients with chronic kidney disease. We discuss the limitations of this approach and the potential value of a more patient-centered paradigm, with a particular focus on the care of older adults with this condition. We conclude by outlining ways in which the evidence-base might be reconfigured to better support real-world treatment decisions in individual patients and summarize relevant ongoing initiatives.

Indexed as

Disease ManagementEvidence-Based MedicineHumansPatient-Centered CareRenal Insufficiency, Chronicevidence-based medicinekidney diseaseolder adultsparadigmpatient-centered care

Identifiers

PMID25637639
PMCPMC4762396

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.