Evidence map›Paper›PMID 25637260›Full record

ReviewExpert review of anti-infective therapy2015

Risk factors for West Nile virus infection and disease in populations and individuals.

Ruth R Montgomery, Kristy O Murray

Open access · greenAbstract readReview
In one paragraph

Review in Expert review of anti-infective therapy, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 34 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
34citing papers in PubMed, 1 pooled it
6.3field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

34 citing papers in PubMed, 1 synthesis or guideline pooled it, 63 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Article
  5. Severe acute respiratory syndrome coronavirus 2 infection and West Nile encephalitis in a patient with chronic kidney disease.Journal of critical care medicine (Universitatea de Medicina si Farmacie din Targu-Mures) · 2025
    Article
  6. Seroprevalence of West Nile Virus in Blood Donors in Mainland Portugal.Tropical medicine and infectious disease · 2025
    Article
  7. Review
  8. Article
  9. Review
  10. Article
  11. Article
  12. Review
  13. Article
  14. Article
  15. Article
  16. Article
  17. Article
  18. Article
  19. Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 2 institutions in 1 country.

Ruth R MontgomeryDepartment of Internal Medicine, Yale School of Medicine, 300 Cedar Street/TAC S413, New Haven, CT 06520-8031, USA.
Kristy O Murray
Baylor College of Medicine · USYale University · US

Funding

Using a tonsil organoid system to probe conditions for the induction of protective antibody and T cell responses to influenza.U19AI057229 · NIAID · STANFORD UNIVERSITY · PI Mark Morris Davis · 2003 to 2026
$88.5M
Systems investigation of vaccine responses in B cell depleted autoimmune patientsU19AI089992 · NIAID · YALE UNIVERSITY · PI David A. Hafler, RUTH R MONTGOMERY · 2010 to 2026
$50.4M
Renal And Neurological Outcomes In Chronically Infected West Nile Virus PatientsR01AI091816 · NIAID · UNIVERSITY OF TEXAS HLTH SCI CTR HOUSTON · PI MURRAY, KRISTY · 2011 to 2014
$1.5M
NIAID NIH HHS AI057229NIAID NIH HHS AI091816NIAID NIH HHS HHSN272201100019CNIAID NIH HHS HHSN272201100019INIAID NIH HHS R01 AI091816NIAID NIH HHS U19 AI057229NIAID NIH HHS U19 AI089992NIAID NIH HHS U19AI089992
6 · The paper itself

Abstract

West Nile virus (WNV) is a mosquito-borne enveloped positive-strand RNA virus that emerged in North America in 1999 in New York City. Over the past 15 years, WNV has become established throughout the USA and has spread into Canada, Mexico and the Caribbean. CDC reports indicate >41,000 clinical cases, including more than 1700 fatalities. An estimated 3 million people in the USA may have been infected to date. Infection with WNV is dependent on many factors including climate, mosquito habitats and immunologically naïve bird populations. In addition, variations within individuals contribute to the risk of severe disease, in particular, advanced age, hypertension, immunosuppression and critical elements of the immune response. Recent advances in technology now allow detailed analysis of complex immune interactions relevant to disease susceptibility.

Indexed as

Adaptive ImmunityAgingAnimalsBiomarkersBirdsCanadaCaribbean RegionCulicidaeHumansImmunity, InnateMexicoRisk FactorsUnited StatesWest Nile FeverWest Nile virusBiomarkersagingavian reservoirepizootic spreadimmune responsemosquito vectormouse modelWest Nile virus

Identifiers

PMID25637260
PMCPMC4939899
OpenAlexW2111158044

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.