Evidence map›Paper›PMID 25636926›Full record

ArticleClinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases2015

Non-tuberculous mycobacterial infections after solid organ transplantation: a survival analysis.

S A Longworth, E A Blumberg, T D Barton, C Vinnard

Open access · bronzeAbstract read
In one paragraph

Article in Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
1.5field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 44 citations in OpenAlex.

  1. Article
  2. Journal of clinical microbiology · 2024
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  5. Open forum infectious diseases · 2022
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  9. Pneumonia due toBMJ case reports · 2021
    Article
  10. Review
  11. Frontiers in medicine · 2018
    Article
  12. Journal of clinical tuberculosis and other mycobacterial diseases · 2017
    Article
  13. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

S A LongworthDepartment of Medicine, Division of Infectious Diseases, Perelman School of Medicine of the University of Pennsylvania, Philadelphia, PA, USA.
E A BlumbergDepartment of Medicine, Division of Infectious Diseases, Perelman School of Medicine of the University of Pennsylvania, Philadelphia, PA, USA.
T D BartonDepartment of Medicine, Division of Infectious Diseases, Perelman School of Medicine of the University of Pennsylvania, Philadelphia, PA, USA.
C VinnardDepartment of Medicine, Division of Infectious Diseases & HIV Medicine, Drexel University College of Medicine, Philadelphia, PA, USA. Electronic address: christopher.vinnard@drexelmed.edu.
University of Pennsylvania · USDrexel University · US

Funding

Rifampicin Malabsorption in HIV+ Patients: Mechanisms and Recovery after HAARTK23AI102639 · NIAID · RBHS-NEW JERSEY MEDICAL SCHOOL · PI VINNARD, CHRISTOPHER · 2014 to 2018
$695k
NIAID NIH HHS K23 AI102639
6 · The paper itself

Abstract

The relationship of non-tuberculous mycobacterial (NTM) infections and survival among solid organ transplant recipients is unknown. We conducted a retrospective cohort study to measure the impact of NTM infection on survival in this patient population, comparing the effect of Mycobacterium abscessus infection with that of infections due to other pathogenic NTM species. We identified 33 patients with NTM infection post-transplantation, 18 with infection that was diagnosed within the first year. Although drug resistance was common among M. abscessus isolates, patients with M. abscessus infection did not have increased mortality compared with patients with other types of NTM infections (p 0.64). In contrast, we observed a significant association overall between early NTM infection and 3-year mortality post-transplantation (hazard ratio 8.76, 95% CI 2.69-28.57). The mortality burden of NTM infection following transplantation may be due to factors other than the virulence of the organisms. Multicentre studies are needed to identify the optimal approach for diagnosing and treating these uncommon but serious infections.

Indexed as

Antitubercular AgentsDrug Resistance, BacterialHumansMycobacterium Infections, NontuberculousNontuberculous MycobacteriaOrgan TransplantationRetrospective StudiesSurvival AnalysisAntitubercular AgentsDrug resistanceepidemiologyMycobacterium abscessusnon-tuberculous mycobacteriatransplantation

Identifiers

PMID25636926
PMCPMC4313615
OpenAlexW2040170253

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.